Postponed Results of Lung Resections for Disseminated Fibrous Cavernous Tuberculosis

D. E. Omelchuk, D. Krasnov, T. I. Petrenko, I. A. Bolshakova, A. A. Kochneva
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Abstract

The objective: to evaluate postponed results of lung resection for disseminated fibrous cavernous tuberculosis.Subjects and Methods. Postponed treatment results were evaluated 3–5 years after surgery, it was the time when patients were taken off the register at TB dispensary (TBD). Inpatient medical records (Form no. 003/u) and outpatient records (Form no. 025/u-04) were used as the source of information.Results. Out of 702 patients for whom postpones results were available, 571/702 (81.3%) were taken off the register 5 years after the surgery due to cure. Relapse with a chronic course of tuberculosis developed in 49/702 (7.0%) patients, and lethal outcome occurred in 82/702 (11.7%) patients (relapse and progression of tuberculosis were the cause in 51 patients, while surgical complications in 31 patients). Over all period of follow-up, 132 tuberculosis relapses were detected, but a significant limitation of this part of the study was the loss of patients for follow-up every year. By the period of “10 years or more”, there were only 139 people available for follow-up and among them 15 (10.8% ) relapses were registered.It was also found that the chances of an unfavorable outcome of tuberculosis treatment were more than 32 times higher in patients with an unfavorable immediate result of the surgery (including not resolved postoperative complications) versus the patients who achieved a favorable result after the surgery (OR = 32.14, 95 % CI 17.57 – 58.78, p<0.001, χ2 =218.8)
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播散性纤维空洞型肺结核肺切除术的延期结果
目的:评估肺切除术治疗播散性纤维空洞型肺结核的延期治疗效果。对术后 3-5 年的延期治疗结果进行评估,即患者从结核病防治所(TBD)登记册中删除的时间。信息来源为住院病历(表号 003/u)和门诊病历(表号 025/u-04)。在有延期结果的 702 名患者中,有 571/702 人(81.3%)在手术 5 年后因治愈而从登记册中删除。49/702(7.0%)名患者的肺结核复发并转为慢性病程,82/702(11.7%)名患者出现死亡(51名患者的病因是肺结核复发和进展,31名患者的病因是手术并发症)。在所有随访期间,共发现 132 例肺结核复发,但这部分研究的一个重要局限是每年都有患者失去随访机会。在 "10 年或 10 年以上 "期间,只有 139 人可以接受随访,其中有 15 人(10.8%)复发。研究还发现,手术后即刻出现不利结果(包括术后并发症未解决)的患者与手术后出现有利结果的患者相比,结核病治疗出现不利结果的几率要高出 32 倍多(OR = 32.14,95 % CI 17.57 - 58.78,P<0.001,χ2 = 218.8)。
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来源期刊
Tuberculosis and Lung Diseases
Tuberculosis and Lung Diseases Medicine-Pulmonary and Respiratory Medicine
CiteScore
1.20
自引率
0.00%
发文量
88
审稿时长
8 weeks
期刊介绍: The Journal is aimed for professional development of researchers, doctors, teachers of medical universities and training institutions. The Journal focuses on the presentation of results of research, case studies, issues of differential diagnostics and treatment in the phthisiologist’s practice, national programs on tuberculosis control in the Russian Federation, WHO strategies, discussion of prevention issues to stop transmission of TB/HIVco-infection, and extrapulmonary tuberculosis.
期刊最新文献
Treatment Results in Patients with Drug Resistant Tuberculosis (MDR, pre-XDR, XDR) and HIV Infection in Stavropol Region Impact of the COVID-19 Restrictive Measures on Tuberculosis Detection among Children and Adolescents Sarcoidosis Phenotyping: Analysis of Current Approaches (Review) Postponed Results of Lung Resections for Disseminated Fibrous Cavernous Tuberculosis Lung Imaging for Suspected Tuberculosis in the Pregnant (Review)
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