Repair and Regeneration of Bone Tissue by Scaffold Implant — A Biomechanical Review

Alessandro Nutini, Sümeyye Tunç
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Abstract

The regeneration and repair of bone tissue is a multiphase process that requires a lot of attention, especially if stimulated through scaffold implantation. This review analyzes the process from both a biological and mechanical point of view through the analysis of the porosity and characteristics of the biomaterials that can provide optimal regeneration of bone tissue and functional vascularization that prevents implant failure. Particular attention is paid to the porosity of the new biomaterials and the related physiological effects and the angiogenesis process that the biomaterials themselves can stimulate, analyzing some of the works present in the literature.
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支架植入物对骨组织的修复和再生--生物力学综述
骨组织的再生和修复是一个多阶段的过程,需要大量的关注,尤其是在通过支架植入刺激的情况下。本综述通过分析生物材料的孔隙率和特性,从生物学和机械学的角度分析了这一过程,认为生物材料可以提供最佳的骨组织再生和功能性血管化,从而防止植入失败。本文特别关注新型生物材料的孔隙率、相关的生理效应以及生物材料本身可刺激的血管生成过程,并对文献中的一些研究成果进行了分析。
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