Problems of Detecting Tuberculosis by Sputum Microscopy in General Medical Services in the Republic of Karelia

Yu. M. Markelov, E. V. Pakhomova, T. Sunchalina
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Abstract

The objective: to determine the effectiveness of detection of patients with pulmonary tuberculosis and prevention of its spread by sputum microscopy in clinical diagnostic laboratories of general medical services of the Republic of Karelia.Results. A reduction in the number of sputum microscopy tests in clinical laboratories of GMS and decrease in the positivity rate to 0.66% was revealed. Among new tuberculosis patients with rifampicin resistance, 51% had abundant bacterial excretion (AFB 2+ and 3+); according to sputum microscopy, tuberculous mycobacteria susceptible to rifampicin were isolated in 38%. In the Republic of Karelia, 31.7% of tuberculosis patients were detected in in-patient units of GMS: 60% of them had cavities, and 28.8% had abundant bacterial excretion (AFB 2+ and 3+). The poor quality of sputum microscopy is the cause of late detection of tuberculosis in the Republic of Karelia and promotes the spread of MDR tuberculosis strains among the population, including nosocomial infection.
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卡累利阿共和国普通医疗服务机构用痰显微镜检测肺结核的问题
目的:确定卡累利阿共和国普通医疗服务临床诊断实验室通过痰显微镜检查发现肺结核患者并防止其传播的有效性。结果显示,普通医疗服务临床实验室的痰显微镜检查次数减少,阳性率降至 0.66%。在对利福平耐药的新肺结核患者中,51%的患者有大量细菌排泄物(AFB 2+ 和 3+);根据痰显微镜检查,38%的患者分离出了对利福平敏感的结核分枝杆菌。在卡累利阿共和国,31.7%的肺结核病人是在 GMS 的住院部发现的:其中 60% 有蛀牙,28.8% 有大量细菌排泄物(AFB 2+ 和 3+)。痰液显微镜检查质量差是卡累利阿共和国肺结核发现较晚的原因,也助长了 MDR 肺结核菌株在人群中的传播,包括院内感染。
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来源期刊
Tuberculosis and Lung Diseases
Tuberculosis and Lung Diseases Medicine-Pulmonary and Respiratory Medicine
CiteScore
1.20
自引率
0.00%
发文量
88
审稿时长
8 weeks
期刊介绍: The Journal is aimed for professional development of researchers, doctors, teachers of medical universities and training institutions. The Journal focuses on the presentation of results of research, case studies, issues of differential diagnostics and treatment in the phthisiologist’s practice, national programs on tuberculosis control in the Russian Federation, WHO strategies, discussion of prevention issues to stop transmission of TB/HIVco-infection, and extrapulmonary tuberculosis.
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