{"title":"Microwave Ablation Therapy for Hepatocellular Carcinoma: The Effect of Metabolic Heat on Temperature Distribution","authors":"Heaven Josiah Harvan, Slamet Wahyudi, Winarto","doi":"10.37934/arfmts.118.2.2433","DOIUrl":null,"url":null,"abstract":"Hepatocellular carcinoma is the main cause of liver cancer and one of the most occurring cancers worldwide. Microwave Ablation (MWA) is a method to destroy cancer cells by heating tumors above 50°C. Cancerous tissues can have high metabolic heat rates and affect temperature gain and distribution in thermal therapies. This research clarifies the metabolic heat effects in MWA therapy of liver cancer. Using Pennes Bioheat transfer equation with finite element numerical method, this research simulates temperature distribution with metabolic heat value ranging from 368,1 W/m3 to 29000 W/m3. The heat generated by metabolic heat is lower than the MWA heat source. However, the temperature increase should be considered as it can increase healthy surrounding tissue temperature to dangerous levels.","PeriodicalId":37460,"journal":{"name":"Journal of Advanced Research in Fluid Mechanics and Thermal Sciences","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Advanced Research in Fluid Mechanics and Thermal Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.37934/arfmts.118.2.2433","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Chemical Engineering","Score":null,"Total":0}
引用次数: 0
Abstract
Hepatocellular carcinoma is the main cause of liver cancer and one of the most occurring cancers worldwide. Microwave Ablation (MWA) is a method to destroy cancer cells by heating tumors above 50°C. Cancerous tissues can have high metabolic heat rates and affect temperature gain and distribution in thermal therapies. This research clarifies the metabolic heat effects in MWA therapy of liver cancer. Using Pennes Bioheat transfer equation with finite element numerical method, this research simulates temperature distribution with metabolic heat value ranging from 368,1 W/m3 to 29000 W/m3. The heat generated by metabolic heat is lower than the MWA heat source. However, the temperature increase should be considered as it can increase healthy surrounding tissue temperature to dangerous levels.
期刊介绍：
This journal welcomes high-quality original contributions on experimental, computational, and physical aspects of fluid mechanics and thermal sciences relevant to engineering or the environment, multiphase and microscale flows, microscale electronic and mechanical systems; medical and biological systems; and thermal and flow control in both the internal and external environment.
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