Influence of Health Literacy on Cancer Prognosis; A Case Report of Childhood Fibrosarcoma

Isabela Magesa, Seth Jotham, S. Mlaga
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Abstract

Background: Cancer is an emerging global public health threat in low- and middle-income countries, and poor health literacy has resulted into poor outcomes due to late diagnosis and care. Fibrosarcoma is among the rare - highly malignant tumor with poor prognosis when diagnosed late. Its survival rate is estimated to be around 20% in Low- and middle-income countries (LMICs) as compared to more than 80% in high-income countries. Case presentation: Herein we report a case of 14-years-old boy with a relapsing mass in his left hand. It was initially thought to be benign and it was resected, but later confirmed by tissue histopathological examination to be an infantile fibrosarcoma. Limb salvage surgery was not possible only to end up with forearm amputation. Discussion: Health literacy of healthcare workers and community at large has an influence on outcome of cancer treatments, it reduces incidences of late diagnoses as primary physicians will have an increased suspicion for malignancies whenever they encounter such a mass especially in children. Most of fibrosarcoma are deemed unresectable at diagnosis hence necessitating a multimodal approach including preoperative cytoreductive therapy and surgery. Conclusion: Fibrosarcoma has good prognosis when diagnosed early. To prevent unfavorable cancer-related outcomes and to have good oncological outcomes; health literacy on soft tissue sarcomas should be promoted especially at the community level as it is the case in other types of cancers.
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健康素养对癌症预后的影响;儿童纤维肉瘤病例报告
背景:在低收入和中等收入国家,癌症是一种新出现的全球性公共健康威胁,由于诊断和治疗较晚,健康知识普及率较低,导致治疗效果不佳。纤维肉瘤是一种罕见的高度恶性肿瘤,如果诊断较晚,预后较差。据估计,中低收入国家的存活率约为 20%,而高收入国家的存活率则超过 80%。病例介绍:在此,我们报告了一例左手有复发性肿块的 14 岁男孩的病例。起初认为是良性肿块并将其切除,但后来经组织病理学检查证实为婴幼儿纤维肉瘤。肢体抢救手术无法进行,只能进行前臂截肢手术。讨论医护人员和整个社区的健康素养对癌症治疗的结果有影响,它可以减少晚期诊断的发生率,因为主治医生在遇到此类肿块(尤其是儿童肿块)时,会增加对恶性肿瘤的怀疑。大多数纤维肉瘤在确诊时被认为是不可切除的,因此需要采取多模式治疗方法,包括术前细胞修复疗法和手术。结论纤维肉瘤如能早期诊断,预后良好。为了预防与癌症相关的不良后果,并获得良好的肿瘤治疗效果,应像其他类型的癌症一样,在社区层面推广有关软组织肉瘤的健康知识。
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