The prognostic relevance of full-thickness burns on ABSI

IF 2.9 3区 医学 Q2 CRITICAL CARE MEDICINE Burns Pub Date : 2024-12-01 Epub Date: 2024-07-06 DOI:10.1016/j.burns.2024.07.001
J. Gorenflo , B. Reichert , German Burn Registry , S. Reif , I.-F. Megas , M. Billner
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Abstract

Introduction

The Abbreviated Burn Severity Index (ABSI) by Tobiasen, which is commonly used to estimate the mortality risk of severely burned patients, calculates an additional point for the existence of full-thickness (third-degree) burns. [1] However, the score does not consider the extent of the body surface affected by third-degree burns. To understand whether there is a way to improve ABSI prediction power, this study aims to determine the influence of full-thickness burns on survival rates and how it affects the predictive precision of the ABSI.

Material and methods

In this study, the statistical evaluation of 2538 patients collected prospectively in the context of the German Burn Registry was carried out. A linear regression analysis was carried out to show the prognostic relevance of full-thickness burns. Age, sex, total body surface area burned (TBSA), and the presence of inhalation injury were also observed as further influencing factors.

Results

Among the 2538 patients meeting our inclusion criteria, full-thickness burns were found in 1233 patients. In patients with a TBSA below 20 %, the extent of full-thickness burns is not relevant to the prognosis in terms of survival probability (p = 0.124). With more than 20 % TBSA, the extent of third-degree burns is of significant relevance (p = 0.000). In patients without full-thickness burns and calculated ABSI values ≥ 12 the survival rate of 46 % was noticeably better than the predicted survival rate of < 10 % according to the ABSI Score, whereas the predicted survival rate in patients with third-degree burns (< 10 %), closely matched the observed survival rate of 11 %.

Conclusion

For patients with a TBSA < 20 %, the presence of full-thickness burns is not relevant for survival. In contrast to this observation, the percentage of full-thickness burns is of crucial prognostic importance for patients with a TBSA of > 20 %. By adjusting the ABSI and taking into account the exact percentage of third-degree burns, an improvement in the prognostic precision of the score could be achieved.
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全层烧伤对 ABSI 预后的影响
Tobiasen的简略烧伤严重程度指数(ABSI)通常用于估计严重烧伤患者的死亡风险,该指数计算了存在全层(三度)烧伤的附加点。然而,该评分并未考虑三度烧伤对体表的影响程度。为了了解是否有办法提高ABSI的预测能力,本研究旨在确定全层烧伤对生存率的影响以及它如何影响ABSI的预测精度。材料和方法在本研究中,对德国烧伤登记处前瞻性收集的2538例患者进行统计评估。进行线性回归分析以显示全层烧伤与预后的相关性。年龄、性别、烧伤总体表面积(TBSA)、是否存在吸入性损伤也是进一步的影响因素。结果在2538例符合纳入标准的患者中,1233例出现全层烧伤。在TBSA低于20%的患者中,全层烧伤的程度与生存概率的预后无关(p = 0.124)。当TBSA超过20%时,三度烧伤的程度具有显著相关性(p = 0.000)。在没有全层烧伤且计算ABSI值≥12的患者中,46%的生存率明显优于预测生存率;ABSI评分为10%,而三度烧伤患者的预测生存率(<;10%),与观察到的11%的存活率非常吻合。结论:TBSA <患者;20%,全层烧伤的存在与生存无关。与这一观察结果相反,全层烧伤的百分比对TBSA为>的患者的预后至关重要。20%。通过调整ABSI并考虑到三度烧伤的确切百分比,可以提高评分的预后精度。
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来源期刊
Burns
Burns 医学-皮肤病学
CiteScore
4.50
自引率
18.50%
发文量
304
审稿时长
72 days
期刊介绍: Burns aims to foster the exchange of information among all engaged in preventing and treating the effects of burns. The journal focuses on clinical, scientific and social aspects of these injuries and covers the prevention of the injury, the epidemiology of such injuries and all aspects of treatment including development of new techniques and technologies and verification of existing ones. Regular features include clinical and scientific papers, state of the art reviews and descriptions of burn-care in practice. Topics covered by Burns include: the effects of smoke on man and animals, their tissues and cells; the responses to and treatment of patients and animals with chemical injuries to the skin; the biological and clinical effects of cold injuries; surgical techniques which are, or may be relevant to the treatment of burned patients during the acute or reconstructive phase following injury; well controlled laboratory studies of the effectiveness of anti-microbial agents on infection and new materials on scarring and healing; inflammatory responses to injury, effectiveness of related agents and other compounds used to modify the physiological and cellular responses to the injury; experimental studies of burns and the outcome of burn wound healing; regenerative medicine concerning the skin.
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