Effect of DU meridian long snake moxibustion on intestinal flora of people with yang deficiency

IF 1.7 Q2 Medicine Advances in integrative medicine Pub Date : 2024-09-01 DOI:10.1016/j.aimed.2024.07.002
Hui Huang , Mengyu Jin , Xiaoyan Gao , Yan Wang , Xiaoming Jiang , Qun Wan , Lele Geng , Xiuwu Hu
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Abstract

Background

The changes of intestinal flora are closely related to the occurrence and development of many diseases. Long snake moxibustion has the functions of strengthening the body resistance, eliminating pathogenic factors and balancing yin and yang, and has been widely used in clinic. This study aimed to explore the effect of long snake moxibustion on intestinal flora in people with yang deficiency constitution.

Methods

The 60 subjects with yang deficiency constitution recruited in a tertiary A-level-integrated traditional Chinese medicine hospital were randomly divided into Du meridian group and non-Du meridian group between May 1, 2021, and July 31, 2021, which were treated once a week for 12 consecutive times. The scores of symptoms of yang deficiency were recorded before and after treatment, fresh stool samples were collected, and the distribution of intestinalflora was detected by 16 S rDNA sequencing technology.

Results

Compared with before treatment, the scores of symptoms of yang deficiency in both groups had a distinct decrease after treatment (P<0.05), and the effect of Du meridian group was better than that of non-Du meridian group. After treatment, the Du meridian group was superior to the non-Du meridian treatment group in the diversity of intestinal flora, the relative abundance of phylum and genus, and the dominant intestinal flora.

Conclusions

Long snake moxibustion on Du meridian can improve the diversity of intestinal flora, promote the balance between beneficial bacteria and harmful bacteria, enhance the integrity of intestinal epithelial barrier and regulate intestinal immunity, thus improving Yang deficiency constitution.

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杜氏经络长蛇灸对阳虚体质者肠道菌群的影响
背景肠道菌群的变化与多种疾病的发生、发展密切相关。长蛇灸具有增强机体抵抗力、消除致病因素、平衡阴阳等作用,已广泛应用于临床。本研究旨在探讨长蛇灸对阳虚体质人群肠道菌群的影响。方法将2021年5月1日至2021年7月31日期间在某三级甲等综合中医院招募的60名阳虚体质受试者随机分为督脉组和非督脉组,每周治疗1次,连续治疗12次。结果与治疗前相比,治疗后两组患者的阳虚症状评分均有明显下降(P<0.05),且本组效果优于非本组。结论长蛇灸督脉可改善肠道菌群的多样性,促进有益菌与有害菌的平衡,增强肠道上皮屏障的完整性,调节肠道免疫功能,从而改善阳虚体质。
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来源期刊
Advances in integrative medicine
Advances in integrative medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-
CiteScore
3.20
自引率
11.80%
发文量
0
审稿时长
15 weeks
期刊介绍: Advances in Integrative Medicine (AIMED) is an international peer-reviewed, evidence-based research and review journal that is multi-disciplinary within the fields of Integrative and Complementary Medicine. The journal focuses on rigorous quantitative and qualitative research including systematic reviews, clinical trials and surveys, whilst also welcoming medical hypotheses and clinically-relevant articles and case studies disclosing practical learning tools for the consulting practitioner. By promoting research and practice excellence in the field, and cross collaboration between relevant practitioner groups and associations, the journal aims to advance the practice of IM, identify areas for future research, and improve patient health outcomes. International networking is encouraged through clinical innovation, the establishment of best practice and by providing opportunities for cooperation between organisations and communities.
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