Evaluation of antimicrobial activity and tensile strength of glass ionomer cement modified with plant extract mixture

Marwa Mohammed Abd eltwab, Mohammed Moustafa Shalaby, Eman Hamdy Mohammed, hanaa farouk mahmoud
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Abstract

Aim: is to assess antimicrobial activity and diametral tensile strength (DTS) of glass ionomer cement (GIC) modified with plant extract mixture (PE). Material and Methods: conventional GIC was utilized. It is treated with PE. Alcoholic extract of Aloe Vera (AVE) was prepared. Using a Soxhlet extractor, an alcoholic extract of Salvadora persica(SPE) was produced. The PE was incorporated to the glass ionomer liquid (GIL).Forty Samples were fabricated using 6 mm diameter and 3 mm thick split-Teflon molds. Samples were divided into two main groups (n=20): group I (antimicrobial test) and group II (diametral tensile strength test). Each group was divided into Four subgroups (n=5) according to liquid composition into: subgroup (A): control subgroup, subgroup (B): 1.5GIL: 1PE, subgroup(C): 1GIL:1PE and subgroup (D): 1GIL:1.5PE. Antimicrobial activity against Streptococcus mutants (SM) was appraised by the agar well diffusion assay method. Universal testing machine was utilized to determine (DTS). Results : One way ANOVA test for quantitative data between the four groups followed by post hoc LSD analysis between each two groups were used. The highest antimicrobial activity was in subgroup ID (1GIL:1.5 PE) and the lowest value was in control subgroup. The highest DTS was in subgroup IIC (1GIL:1PE) and lowest was in control subgroup. Conclusions: Plant extract significantly improved the antimicrobial activity of GIC against SM. The DTS of GIC was improved within limits by addition of PE only up to (1 GIL: 1 PE).
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评估用植物提取物混合物改性的玻璃离子聚合物水泥的抗菌活性和拉伸强度
目的:评估用植物提取混合物(PE)改性的玻璃离子水泥(GIC)的抗菌活性和直径拉伸强度(DTS)。材料和方法:使用传统的 GIC。用 PE 对其进行处理。制备芦荟酒精提取物(AVE)。使用索氏萃取器,制备出 Salvadora persica 的酒精萃取物(SPE)。使用直径为 6 毫米、厚度为 3 毫米的分体式聚四氟乙烯模具制作了 40 个样品。样品分为两大组(n=20):第一组(抗菌测试)和第二组(直径拉伸强度测试)。每组按液体成分分为四个子组(n=5):子组(A):对照子组;子组(B):1.5GIL:1PE 子组;子组(C):1.5GIL:1PE 子组;子组(D):1.5GIL:1PE 子组:1.5GIL:1PE,子组(C):1GIL:1PE 和子组(D):1GIL:1.5PE。琼脂井扩散试验法评估了对链球菌突变体(SM)的抗菌活性。利用万能试验机测定(DTS)。结果:对四组之间的定量数据进行了单向方差分析,然后对每两组之间的数据进行了事后 LSD 分析。抗菌活性最高的是 ID 亚组(1GIL:1.5 PE),最低的是对照亚组。DTS值最高的是IIC亚组(1GIL:1PE),最低的是对照亚组。结论植物提取物明显提高了 GIC 对 SM 的抗菌活性。加入 PE 后,GIC 的 DTS 在一定范围内得到改善,最高可达(1 GIL:1 PE)。
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