The Association between S.T.O.N.E. Nephrolithometry Score and Hemoglobin Drop in Patients Undergoing Percutaneous Nephrolithotomy

Mohan Khadka, K. K. Bhomi, Amit Shrestha, Bineet Thapa
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Abstract

Nephrolithiasis is a very common condition with significant burden to patients. Percutaneous nephrolithotomy (PCNL) is safe procedure considered as gold standard for large renal stones. The most common complication of PCNL is bleeding which can require blood transfusion to angioembolization and may even need nephrectomy. The purpose of this study is to assess if STONE Nephrolithometry Score can predict hemoglobin drop in PCNL procedure. A total of 104 patients who underwent PCNL during one year period from October of 2022 to September of 2023 were taken using consecutive sampling method. All patients with renal stones underwent routine blood tests including complete blood counts, renal function and electrolytes. CT scans were then done and STONE nephrolithometry Score was evaluated. PCNL was performed and hemoglobin investigation was sent at 24 hours postoperatively. The two data were compared with the STONE nephrolithometry Score and other factors. More than three-fourths (78.8%) of the patients had comorbidities with hypertension being the commonest (76.9%). There was a significant association of drop of hemoglobin more than 1 g/dl with age <30 years (p <0.034), higher preoperative hemoglobin (p <0.046), larger stone size (p <0.001), shorter tract length (p=0.017) and STONE Score greater than 10 (p<0.001). On correlation study only STONE score (p = 0.015) and larger stone size (p = 0.002) were associated with hemoglobin drops of more than 1 g/dl. STONE Nephrolithometry score is a good predictor of bleeding complications during PCNL and higher score is associated with more drop in hemoglobin levels.
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经皮肾镜取石术患者的 S.T.O.N.E. 肾镜评分与血红蛋白下降之间的关系
肾结石是一种非常常见的疾病,给患者带来沉重负担。经皮肾镜取石术(PCNL)是一种安全的手术,被认为是治疗大块肾结石的金标准。PCNL 最常见的并发症是出血,可能需要输血或血管栓塞,甚至可能需要进行肾切除术。本研究旨在评估 STONE 肾石测量评分是否能预测 PCNL 手术中的血红蛋白下降。本研究采用连续取样法,在2022年10月至2023年9月的一年时间内,共抽取了104名接受PCNL手术的患者。所有肾结石患者都接受了血常规检查,包括全血细胞计数、肾功能和电解质。然后进行 CT 扫描并评估 STONE 肾结石评分。术后 24 小时进行 PCNL 和血红蛋白检查。将这两项数据与 STONE 肾石测量评分和其他因素进行比较。超过四分之三(78.8%)的患者患有合并症,其中高血压最为常见(76.9%)。血红蛋白下降超过 1 克/分升与年龄小于 30 岁(P <0.034)、术前血红蛋白较高(P <0.046)、结石较大(P <0.001)、结石道长度较短(P=0.017)和 STONE 评分大于 10(P <0.001)有明显关联。在相关性研究中,只有 STONE 评分(p = 0.015)和结石体积较大(p = 0.002)与血红蛋白下降超过 1 g/dl 有关。STONE 肾石测量评分是 PCNL 期间出血并发症的良好预测指标,评分越高,血红蛋白水平下降越多。
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