{"title":"The synthesis of iron oxide nanoparticles in confined space","authors":"Yifan Zhao, Linyuan Wu, Yan Li, Yu Mao, Ning Gu","doi":"10.1007/s40843-024-2875-3","DOIUrl":null,"url":null,"abstract":"<p>This review delves into the synthesis of iron oxide nanoparticles (IONPs), a pioneering nanomaterial in biomedical applications. It highlights the limitations of traditional synthetic methods, such as co-precipitation, thermal decomposition, sol–gel method, and hydrothermal synthesis, particularly their inability to fully control substance exchanges, impacting the purity and functionality of IONPs. Confined-space synthesis was proposed as a solution, offering precise control over the chemical processes and enhanced properties of IONPs. This approach parallels natural biosynthesis processes in cells, leveraging nanoreactors for controlled reactions. This review explores various strategies for confined-space synthesis in laboratory settings, aiming to advance the understanding and application of nanoreactors in IONPs production, thereby paving the way for the development of nanomaterials with more excellent biocompatibility and therapeutic effect.</p>","PeriodicalId":773,"journal":{"name":"Science China Materials","volume":null,"pages":null},"PeriodicalIF":6.8000,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Science China Materials","FirstCategoryId":"88","ListUrlMain":"https://doi.org/10.1007/s40843-024-2875-3","RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
This review delves into the synthesis of iron oxide nanoparticles (IONPs), a pioneering nanomaterial in biomedical applications. It highlights the limitations of traditional synthetic methods, such as co-precipitation, thermal decomposition, sol–gel method, and hydrothermal synthesis, particularly their inability to fully control substance exchanges, impacting the purity and functionality of IONPs. Confined-space synthesis was proposed as a solution, offering precise control over the chemical processes and enhanced properties of IONPs. This approach parallels natural biosynthesis processes in cells, leveraging nanoreactors for controlled reactions. This review explores various strategies for confined-space synthesis in laboratory settings, aiming to advance the understanding and application of nanoreactors in IONPs production, thereby paving the way for the development of nanomaterials with more excellent biocompatibility and therapeutic effect.
期刊介绍:
Science China Materials (SCM) is a globally peer-reviewed journal that covers all facets of materials science. It is supervised by the Chinese Academy of Sciences and co-sponsored by the Chinese Academy of Sciences and the National Natural Science Foundation of China. The journal is jointly published monthly in both printed and electronic forms by Science China Press and Springer. The aim of SCM is to encourage communication of high-quality, innovative research results at the cutting-edge interface of materials science with chemistry, physics, biology, and engineering. It focuses on breakthroughs from around the world and aims to become a world-leading academic journal for materials science.