Fractal Changes of the Retinal Microvasculature in Birdshot Chorioretinopathy.

IF 0.9 4区医学 Q4 OPHTHALMOLOGY Ophthalmic surgery, lasers & imaging retina Pub Date : 2024-11-01 Epub Date: 2024-07-01 DOI:10.3928/23258160-20240528-02

Kaersti L Rickels, Marco Ji, Ahmed Shakarchi, Michalis Georgiou, Sami H Uwaydat, Ahmed B Sallam

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Abstract

Background and objective: Retinal vascular disorders are associated with lower fractal dimension (FD). We analyzed FD in birdshot chorioretinopathy (BSCR).

Patients and methods: This was a retrospective cohort study. We performed optical coherence tomography angiography (OCTA) and analyzed FD of the superficial capillary plexus (SCP), deep capillary plexus (DCP), and choriocapillaris (CC) using ImageJ. For each vascular layer, we analyzed the presence of BSCR, subjects' age, sex, and presence of diabetes mellitus to determine which may predict lower FD.

Results: We compared 28 eyes (14 patients) with BSCR to 34 control eyes (17 patients). Mean FD of BSCR was lower in SCP (1.584 [± 0.126] vs 1.706 [± 0.118], P < 0.001), DCP (1.637 [± 0.134] vs 1.780 [± 0.096], P < 0.001), and CC (1.884 [± 0.063] vs 1.917 [± 0.047], P = 0.036). FD of SCP was lower per increasing year (0.005 [P = 0.014]). Male patients had lower FD-DCP (0.101 [P = 0.043]).

Conclusion: In BSCR, fractal analysis showed significant involvement of the SCP, DCP, and to a lesser extent the CC. [Ophthalmic Surg Lasers Imaging Retina 2024;55:646-651.].

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鸟枪状脉络膜视网膜病变中视网膜微血管的分形变化

背景和目的：视网膜血管疾病与较低的分形维度（FD）有关。我们分析了鸟枪状脉络膜视网膜病变（BSCR）的断裂维度：这是一项回顾性队列研究。我们进行了光学相干断层血管造影（OCTA），并使用 ImageJ 分析了浅层毛细血管丛（SCP）、深层毛细血管丛（DCP）和绒毛膜（CC）的 FD。对于每个血管层，我们分析了是否存在 BSCR、受试者的年龄、性别和是否患有糖尿病，以确定哪些因素可以预测较低的 FD：我们将 28 只患有 BSCR 的眼睛（14 名患者）与 34 只对照组眼睛（17 名患者）进行了比较。在 SCP（1.584 [± 0.126] vs 1.706 [± 0.118]，P < 0.001）、DCP（1.637 [± 0.134] vs 1.780 [± 0.096]，P < 0.001）和 CC（1.884 [± 0.063] vs 1.917 [± 0.047]，P = 0.036）中，BSCR 的平均 FD 较低。SCP的FD每增加一年降低（0.005 [P = 0.014]）。男性患者的 FD-DCP 较低（0.101 [P = 0.043]）：结论：在 BSCR 中，分形分析表明 SCP、DCP 以及较小程度上的 CC 受到了严重影响。[眼科手术激光成像视网膜2024;55:XX-XX]。

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来源期刊

Ophthalmic surgery, lasers & imaging retina OPHTHALMOLOGY-SURGERY

CiteScore

1.80

自引率

0.00%

发文量

期刊介绍： OSLI Retina focuses exclusively on retinal diseases, surgery and pharmacotherapy. OSLI Retina will offer an expedited submission to publication effort of peer-reviewed clinical science and case report articles. The front of the journal offers practical clinical and practice management features and columns specific to retina specialists. In sum, readers will find important peer-reviewed retina articles and the latest findings in techniques and science, as well as informative business and practice management features in one journal.