Near-infrared reactance spectroscopy-derived visceral adipose tissue for the assessment of metabolic syndrome in a multi-ethnic sample of young adults

IF 1.6 4区医学 Q1 ANTHROPOLOGY American Journal of Human Biology Pub Date : 2024-07-22 DOI:10.1002/ajhb.24141

Austin J. Graybeal, Caleb F. Brandner, Havens L. Wise, Alex Henderson, Ryan S. Aultman, Anabelle Vallecillo-Bustos, Ta' Quoris A. Newsome, Diavion Stanfield, Jon Stavres

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Abstract

Objectives

Visceral adipose tissue (VAT) is highly associated with metabolic syndrome (MetS), which is rapidly increasing in young adults. However, accessible VAT measurement methods are limited, restricting the use of VAT in early detection. This cross-sectional study sought to determine if near-infrared reactance spectroscopy (NIRS)-derived VAT (VAT_NIRS) was associated with MetS in a multi-ethnic sample of young adults.

Methods

A total of 107 male and female (F:62, M:45) participants (age: 23.0 ± 4.3y; BMI: 27.1 ± 6.6 kg/m²) completed measurements of fasting blood pressure, blood glucose (FBG), blood lipids, and anthropometric assessments including waist circumference and VAT_NIRS. MetS severity (MetS_index) was calculated from the aforementioned risk factors using sex and race-specific equations.

Results

VAT_NIRS was higher in participants with, and at risk for, MetS compared to those with lower risks (all p < .001). VAT_NIRS was positively associated with MetS_index for all groups (all p < .001). VAT_NIRS showed positive associations with systolic (SBP), diastolic (DBP), and mean arterial pressure (MAP), LDL-C and LDL-C-related biomarkers, and FBG; and negative associations with HDL-C and HDL-C-to-total cholesterol ratio (all p < .050). Associations between VAT_NIRS and blood pressure for females, and LDL-C and LDL-C-related biomarkers for males, were nonsignificant (all p > .050). VAT_NIRS was positively associated with DBP in African–American participants, and SBP in White participants, resulting in positive associations with MAP for both groups (all p < .050).

Conclusions

VAT_NIRS is associated with MetS and individual MetS risks factors in a multi-ethnic sample of young adults; providing a noninvasive, cost-effective, portable, and accessible method that may assist in the early detection of MetS and other cardiometabolic abnormalities.

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利用近红外反应光谱分析内脏脂肪组织，评估多种族年轻成年人的代谢综合征。

目的：内脏脂肪组织（VAT）与代谢综合征（MetS）密切相关，而代谢综合征在年轻人中正在迅速增加。然而，可用的内脏脂肪组织测量方法有限，限制了内脏脂肪组织在早期检测中的应用。这项横断面研究试图确定近红外反应光谱法（NIRS）得出的 VAT（VATNIRS）是否与多种族年轻成人样本中的 MetS 相关：共有 107 名男女参与者（女：62，男：45）（年龄：23.0 ± 4.3 岁；体重指数：27.1 ± 6.6 kg/m2）完成了空腹血压、血糖 (FBG)、血脂以及包括腰围和 VATNIRS 在内的人体测量评估。MetS 严重程度（MetSindex）是根据上述风险因素采用性别和种族特异性方程计算得出的：结果：与风险较低的参与者相比，患有 MetS 或有 MetS 风险的参与者的 VATNIRS 值更高（所有组别中，近红外光谱与 MetS 指数呈正相关（所有组别中，近红外光谱与收缩压 (SBP)、舒张压 (DBP) 和平均动脉压 (MAP)、低密度脂蛋白胆固醇 (LDL-C) 和与 LDL-C 相关的生物标志物以及血脂 (FBG) 呈正相关），而与高密度脂蛋白胆固醇 (HDL-C) 和高密度脂蛋白胆固醇相关的生物标志物呈负相关（所有组别中，近红外光谱与 MetS 指数呈正相关）；与高密度脂蛋白胆固醇（HDL-C）和高密度脂蛋白胆固醇（HDL-C）与总胆固醇的比值呈负相关（女性的近红外光谱与血压、男性的低密度脂蛋白胆固醇（LDL-C）和低密度脂蛋白胆固醇（LDL-C）相关生物标志物的比值均不显著（均 p > .050).非裔美国人的 VATNIRS 与 DBP 呈正相关，而白人参与者则与 SBP 呈正相关，从而导致这两组人的 MAP 呈正相关（所有 p 均为结论）：在多种族年轻成年人样本中，VATNIRS 与 MetS 和个别 MetS 危险因素相关；提供了一种无创、经济、便携、易用的方法，可帮助早期检测 MetS 和其他心脏代谢异常。

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来源期刊

American Journal of Human Biology 生物-生物学

CiteScore

4.80

自引率

13.80%

发文量

124

审稿时长

4-8 weeks

期刊介绍： The American Journal of Human Biology is the Official Journal of the Human Biology Association. The American Journal of Human Biology is a bimonthly, peer-reviewed, internationally circulated journal that publishes reports of original research, theoretical articles and timely reviews, and brief communications in the interdisciplinary field of human biology. As the official journal of the Human Biology Association, the Journal also publishes abstracts of research presented at its annual scientific meeting and book reviews relevant to the field. The Journal seeks scholarly manuscripts that address all aspects of human biology, health, and disease, particularly those that stress comparative, developmental, ecological, or evolutionary perspectives. The transdisciplinary areas covered in the Journal include, but are not limited to, epidemiology, genetic variation, population biology and demography, physiology, anatomy, nutrition, growth and aging, physical performance, physical activity and fitness, ecology, and evolution, along with their interactions. The Journal publishes basic, applied, and methodologically oriented research from all areas, including measurement, analytical techniques and strategies, and computer applications in human biology. Like many other biologically oriented disciplines, the field of human biology has undergone considerable growth and diversification in recent years, and the expansion of the aims and scope of the Journal is a reflection of this growth and membership diversification. The Journal is committed to prompt review, and priority publication is given to manuscripts with novel or timely findings, and to manuscripts of unusual interest.