Valeria Pergola, Nicola Pradegan, Elena Cozza, Dan Alexandru Cozac, Irene Cao, Chiara Tessari, Maria Teresa Savo, Giuseppe Toscano, Annalisa Angelini, Vincenzo Tarzia, Giuseppe Tarantini, Francesco Tona, Giorgio De Conti, Sabino Iliceto, Gino Gerosa, Raffaella Motta
{"title":"Redefining CAV surveillance strategies: Benefits of CCTA vs. ICA.","authors":"Valeria Pergola, Nicola Pradegan, Elena Cozza, Dan Alexandru Cozac, Irene Cao, Chiara Tessari, Maria Teresa Savo, Giuseppe Toscano, Annalisa Angelini, Vincenzo Tarzia, Giuseppe Tarantini, Francesco Tona, Giorgio De Conti, Sabino Iliceto, Gino Gerosa, Raffaella Motta","doi":"10.1016/j.jcct.2024.07.004","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Cardiac allograft vasculopathy (CAV) assessment post-heart transplantation (HT) typically relies on invasive coronary angiography (ICA). However, cardiac computed tomography angiography (CCTA) is emerging as a promising alternative due to its potential benefits in economic, safety, and logistical aspects. This study aimed to evaluate the impact of a CCTA program on these aspects in CAV surveillance post-HT.</p><p><strong>Methods: </strong>A retrospective single-center study was conducted between March 2021 and February 2023, involving HT patients who underwent either CCTA or ICA.</p><p><strong>Results: </strong>Among 260 patients undergoing CAV surveillance, 115 (44.2%) patients underwent CCTA, and 145 (55.8%) patients underwent ICA. The CCTA group showed incurred lower overall costs (p < 0.0001) and shorter hospitalization times (p < 0.0001) compared to the ICA group. In terms of safety, CCTA surveillance required significantly lower contrast volumes (p < 0.0001) and lower effective doses (p = 0.03).</p><p><strong>Conclusion: </strong>CCTA emerges as a safe and cost-effective non-invasive alternative for CAV surveillance post-HT, outperforming ICA in terms of safety, logistical aspects, and economic burden.</p>","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of cardiovascular computed tomography","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.jcct.2024.07.004","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Cardiac allograft vasculopathy (CAV) assessment post-heart transplantation (HT) typically relies on invasive coronary angiography (ICA). However, cardiac computed tomography angiography (CCTA) is emerging as a promising alternative due to its potential benefits in economic, safety, and logistical aspects. This study aimed to evaluate the impact of a CCTA program on these aspects in CAV surveillance post-HT.
Methods: A retrospective single-center study was conducted between March 2021 and February 2023, involving HT patients who underwent either CCTA or ICA.
Results: Among 260 patients undergoing CAV surveillance, 115 (44.2%) patients underwent CCTA, and 145 (55.8%) patients underwent ICA. The CCTA group showed incurred lower overall costs (p < 0.0001) and shorter hospitalization times (p < 0.0001) compared to the ICA group. In terms of safety, CCTA surveillance required significantly lower contrast volumes (p < 0.0001) and lower effective doses (p = 0.03).
Conclusion: CCTA emerges as a safe and cost-effective non-invasive alternative for CAV surveillance post-HT, outperforming ICA in terms of safety, logistical aspects, and economic burden.
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