Effect of quince seed gum (QSG) on the performance of injectable hyaluronic acid hydrogels in terms of the rheological, morphological, and mechanical aspect.

IF 1.3 4区 化学 Q3 CHEMISTRY, MULTIDISCIPLINARY Turkish Journal of Chemistry Pub Date : 2024-05-29 eCollection Date: 2024-01-01 DOI:10.55730/1300-0527.3669
Serdar Kolay, Nilhan Kayaman Apohan, Erdinç Babuç, Gökay Gün
{"title":"Effect of quince seed gum (QSG) on the performance of injectable hyaluronic acid hydrogels in terms of the rheological, morphological, and mechanical aspect.","authors":"Serdar Kolay, Nilhan Kayaman Apohan, Erdinç Babuç, Gökay Gün","doi":"10.55730/1300-0527.3669","DOIUrl":null,"url":null,"abstract":"<p><p>Injectable hydrogels play an important role in tissue engineering as a filling and repairing material. This study aimed to develop a new injectable hydrogel based on hyaluronic acid (HA) and quince seed gum (QSG) and investigate the effect of QSG on hydrogel performance. The amount of unreacted 1,4-Butanediol diglycidyl ether is maintained at an undetectable level for HA-QSG hydrogels. Amino acid analysis showed that the HA-QSG hydrogel had rich amino acid concentrations of leucine, arginine, and valine. After thermal sterilization, the elastic modulus of HA-QSG gels for dermal and intraarticular filler applications is 63 Pa and 92 Pa, respectively. Pore size was found below 200 μm and the dense homogeneous pore structure was observed.</p>","PeriodicalId":23367,"journal":{"name":"Turkish Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":1.3000,"publicationDate":"2024-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11265888/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Turkish Journal of Chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.55730/1300-0527.3669","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0

Abstract

Injectable hydrogels play an important role in tissue engineering as a filling and repairing material. This study aimed to develop a new injectable hydrogel based on hyaluronic acid (HA) and quince seed gum (QSG) and investigate the effect of QSG on hydrogel performance. The amount of unreacted 1,4-Butanediol diglycidyl ether is maintained at an undetectable level for HA-QSG hydrogels. Amino acid analysis showed that the HA-QSG hydrogel had rich amino acid concentrations of leucine, arginine, and valine. After thermal sterilization, the elastic modulus of HA-QSG gels for dermal and intraarticular filler applications is 63 Pa and 92 Pa, respectively. Pore size was found below 200 μm and the dense homogeneous pore structure was observed.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
榅桲籽胶(QSG)对可注射透明质酸水凝胶流变学、形态学和力学性能的影响。
可注射水凝胶作为填充和修复材料在组织工程中发挥着重要作用。本研究旨在开发一种基于透明质酸(HA)和榅桲籽胶(QSG)的新型可注射水凝胶,并研究 QSG 对水凝胶性能的影响。HA-QSG 水凝胶中未反应的 1,4-丁二醇二缩水甘油醚的含量保持在检测不到的水平。氨基酸分析表明,HA-QSG 水凝胶富含亮氨酸、精氨酸和缬氨酸。经过热消毒后,用于皮肤和关节内填充物的 HA-QSG 水凝胶的弹性模量分别为 63 Pa 和 92 Pa。孔径小于 200 μm,并观察到致密均匀的孔隙结构。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Turkish Journal of Chemistry
Turkish Journal of Chemistry 化学-工程:化工
CiteScore
2.40
自引率
7.10%
发文量
87
审稿时长
3 months
期刊介绍: The Turkish Journal of Chemistry is a bimonthly multidisciplinary journal published by the Scientific and Technological Research Council of Turkey (TÜBİTAK). The journal is dedicated to dissemination of knowledge in all disciplines of chemistry (organic, inorganic, physical, polymeric, technical, theoretical and analytical chemistry) as well as research at the interface with other sciences especially in chemical engineering where molecular aspects are key to the findings. The journal accepts English-language original manuscripts and contribution is open to researchers of all nationalities. The journal publishes refereed original papers, reviews, letters to editor and issues devoted to special fields. All manuscripts are peer-reviewed and electronic processing ensures accurate reproduction of text and data, plus publication times as short as possible.
期刊最新文献
Corrigendum to "Polybrominated methoxy- and hydroxynaphthalenes" [Turkish Journal of Chemistry 40 (2) 2016 332-346 ]. Synthesis and characterization of new hexahydroquinoline derivatives and evaluation of their cytotoxicity, intracellular ROS production, and inhibitory effects on inflammatory mediators. Identification of blood at simulated crime scenes using silver nanoparticles with SERS. Magnetic solid-phase extraction technique based on Fe3O4@coPPy-PTH nanocomposite for extraction of cobalt, chromium, and nickel prior to determination by microsample injection system-flame atomic absorption spectrometry in alcoholic and nonalcoholic beverages. Synthesis of 3-methyl-3-buten-1-ol by supercritical CO2 in coordination with HZSM-5-catalyzed formaldehyde-isobutene Prins reaction.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1