Local anesthesia nerve block for managing burning mouth syndrome: a scoping review

Camila Barcellos Calderipe DDS, Laura Borges Kirschnick DDS MSc, Thaís Cristina Esteves Pereira DDS, Erison Santana dos Santos DDS MSc, Ana Carolina Uchoa Vasconcelos DDS MSc PhD, Marcio Ajudarte Lopes DDS MSc PhD, Nathaniel Simon Treister DMD DMSc, Alan Roger Santos-Silva DDS MSc PhD FAAOM
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Abstract

To assess the clinical scenarios in which nerve blocks are employed in the context of burning mouth syndrome (BMS). This scoping review followed the PRISMA-ScR. A protocol was generated on Open Science Framework. Electronic searches were performed in the following databases: PubMed, Scopus, EMBASE, Web of Science, LILACS, and Cochrane, in addition to the grey literature and citations from Grémeau-Richard et al. (2010). Nerve blocks were used for treatment purposes in all cases. The mandibular nerve and the stellate ganglion were both blocked in 50% studies, while the maxillary nerve and lingual nerve were blocked in 25% study each. The anesthetics used were lidocaine (50%) and bupivacaine (50%). Relief was generally reported after immediate block, and at a mean follow-up of 4.5 weeks, there was considerable improvement compared to the initial conditions when the mandibular and/or maxillary nerve were targeted. The use of nerve blocks has been employed in the treatment of patients with refractory BMS. Clinical studies with standardized methodology are necessary to validate and understand the potential role of mandibular and maxillary nerve block in this setting.
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局部麻醉神经阻滞治疗烧灼口腔综合征:范围综述
评估烧灼口腔综合征(BMS)中使用神经阻滞的临床情况。本范围界定综述遵循 PRISMA-ScR。在 "开放科学框架"(Open Science Framework)上生成了一份协议。在以下数据库中进行了电子检索:PubMed、Scopus、EMBASE、Web of Science、LILACS 和 Cochrane,以及灰色文献和 Grémeau-Richard 等人(2010 年)的引文。所有病例均采用神经阻滞治疗。50%的研究对下颌神经和星状神经节均进行了阻滞,而上颌神经和舌神经阻滞的研究各占25%。使用的麻醉剂为利多卡因(50%)和布比卡因(50%)。据报道,立即阻滞后症状普遍得到缓解,在平均 4.5 周的随访中,与针对下颌神经和/或上颌神经的初始条件相比,症状有了显著改善。神经阻滞已被用于治疗难治性 BMS 患者。为了验证和了解下颌和上颌神经阻滞在这种情况下的潜在作用,有必要采用标准化方法进行临床研究。
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