A handheld laser-cut device for the size-controlled assembly and electrical characterisation of lipid bilayers†

IF 3.5 Q2 CHEMISTRY, ANALYTICAL Sensors & diagnostics Pub Date : 2024-07-24 DOI:10.1039/D4SD00076E
Ji Huang, Yuval Elani and Mark S. Friddin
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Abstract

We report the rapid fabrication of a handheld laser cut platform that can support the assembly, functionalisation, size-control and electrical characterisation of lipid bilayers. We achieve this by building a modular DIY platform that can support the lowering of a Ag/AgCl electrode through a phase transfer column consisting of an upper oil phase containing lipids, and a lower aqueous phase containing buffer.

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用于控制脂质双分子层的尺寸和电学特性的手持式激光切割装置
我们报告了手持激光切割平台的快速制造过程,该平台可支持脂质双层膜的组装、功能化、尺寸控制和电学表征。我们通过构建模块化 DIY 平台来实现这一目标,该平台可支持通过由含有脂质的上层油相和含有缓冲液的下层水相组成的相转移柱来降低银/氯化银电极。
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