Polydopamine-wrapped copper ferrite nanoparticle electrochemical sensor for detection of chloramphenicol

Abstract

Environmental and public health risks may arise from the presence of antibiotic residues, and specifically chloramphenicol in food samples. Therefore, it is quite important for researchers to detect chloramphenicol. In this work, PDA@CuFe₂O₄ nanoparticles were synthesized and characterizsed. The PDA@CuFe₂O₄ nanoparticles that had been prepared were used to create PDA@CuFe₂O₄/GCE, which was then used to detect chloramphenicol electrochemically in a 0.1 M phosphate buffer solution (pH 7). The study focused on the electrochemical properties, including changes in scan rate, sensing, and pH influence. Compared to the unmodified electrode, the PDA@CuFe₂O₄/GCE electrode exhibits better sensing properties. The advantage of the PDA@CuFe₂O₄/GCE electrode is that it shows unique electrochemical sensing toward individual and chloramphenicol detection; for instance, it has a low detection of 0.12µM for chloramphenicol detection and a high sensitivity of 16.25A µM⁻¹ cm⁻² for chloramphenicol detection.

Graphical abstract