Importance of In Vitro Embryo Model Procedure Standardization

IF 2.6 4区 医学 Q2 MEDICAL LABORATORY TECHNOLOGY Journal of Clinical Laboratory Analysis Pub Date : 2024-07-29 DOI:10.1002/jcla.25082
Kubilay Doğan Kılıç, Zeynep Simge Yılmaz
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Abstract

In vivo studies offer a detailed understanding of organism functioning, surpassing the insights provided by in vitro studies. These experiments are crucial for comprehending disease emergence, progression, and associated mechanisms in humans, as well as for developing treatments. When choosing experimental models, factors such as genomic similarity, physiological relevance, ethical appropriateness, and economic feasibility must be considered. Standardized protocols enhance the reliability, and reproducibility of scientific methods, promoting the assessment of research in the scientific literature. Researchers conducting embryo studies should establish and document standardized protocols for increased data comparability. Standardization is vital for scientific validity, reproducibility, and comparability in both in vivo and in vitro studies, ensuring the accuracy and reliability of experimental results and advancing scientific knowledge.

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体外胚胎模型程序标准化的重要性。
体内研究能够详细了解生物体的功能,其洞察力远远超过体外研究。这些实验对于理解人类疾病的发生、发展和相关机制以及开发治疗方法至关重要。在选择实验模型时,必须考虑基因组相似性、生理相关性、伦理适宜性和经济可行性等因素。标准化方案可提高科学方法的可靠性和可重复性,促进科学文献对研究的评估。进行胚胎研究的研究人员应建立和记录标准化方案,以提高数据的可比性。标准化对于体内和体外研究的科学有效性、可重复性和可比性至关重要,可确保实验结果的准确性和可靠性,并促进科学知识的发展。
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来源期刊
Journal of Clinical Laboratory Analysis
Journal of Clinical Laboratory Analysis 医学-医学实验技术
CiteScore
5.60
自引率
7.40%
发文量
584
审稿时长
6-12 weeks
期刊介绍: Journal of Clinical Laboratory Analysis publishes original articles on newly developing modes of technology and laboratory assays, with emphasis on their application in current and future clinical laboratory testing. This includes reports from the following fields: immunochemistry and toxicology, hematology and hematopathology, immunopathology, molecular diagnostics, microbiology, genetic testing, immunohematology, and clinical chemistry.
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