Nanotechnology applications in breast implant manufacturing for improved durability and functionality

Busola Sulaimon
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Abstract

Breast implants are often used in restorative and cosmetic surgeries. However, the materials used for implants today could be better regarding biocompatibility and mechanical strength. It is possible to make composite biomaterials out of nanomaterials with better mechanical qualities than common implant materials like silicone elastomers and saline-filled shells. Researchers have found that adding carbon nanotubes, graphene, and hydroxyapatite nanoparticles to the shells of metal and silicone implants makes them much stronger, more flexible, and less likely to break. Researchers are also looking into polymer nanocomposites made of polycaprolactone and polylactic acid to see if they can break down better and integrate better with tissues. Changing the surface of implants at the nanoscale level can make them more biocompatible by controlling how proteins stick to the material and how cells interact with it. Animal tests with nanocoatings of polyacrylate, chitosan, and hyaluronic acid showed that they lowered the formation of capsules and inflammation. Antimicrobial nanoparticles, such as silver, zinc oxide, and antibiotics, are attached to the surfaces of implants to protect against infections and release drugs locally. Nanocontrast agents are used in high-resolution MRI and ultrasound images of implant shell integrity to get new imaging and diagnosis tools. By tracking biomarkers, nanostructured sensors could be used to find seromas, ruptures, and device failures with little to no damage. Much work has been done to show that different nanotechnologies can help breast implants in a pre-clinical setting. However, problems with regulation and standardization still need to be fixed before the implants can be used in people and made in large quantities. The process needs to be improved even more to make a lot of nanocomposite and etched surfaces. To make sure patients are safe, it is also important to do long-term biocompatibility and nanotoxicology tests. Nanotechnology has a lot of promise to change the way breast implants are made so that they look better and improve people's quality of life. This review examines nanotechnology's emerging applications for enhancing breast implants' durability and performance.
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在乳房植入物制造中应用纳米技术,提高耐用性和功能性
乳房植入物通常用于修复和美容手术。然而,如今用于植入物的材料在生物相容性和机械强度方面可以做得更好。利用纳米材料制造复合生物材料是有可能的,这种材料的机械性能优于硅树脂弹性体和盐水填充外壳等普通植入材料。研究人员发现,将碳纳米管、石墨烯和羟基磷灰石纳米颗粒添加到金属和硅酮植入物的外壳中,可使其更加坚固、灵活,不易破裂。研究人员还在研究由聚己内酯和聚乳酸制成的聚合物纳米复合材料,看它们是否能更好地分解并与组织更好地结合。通过控制蛋白质如何粘附在材料上以及细胞如何与材料相互作用,在纳米级水平上改变植入物的表面可以使其更具生物相容性。使用聚丙烯酸酯、壳聚糖和透明质酸的纳米涂层进行的动物试验表明,它们能减少囊肿的形成和炎症的发生。银、氧化锌和抗生素等抗菌纳米粒子被附着在植入物表面,以防止感染并在局部释放药物。纳米对比剂被用于植入物外壳完整性的高分辨率核磁共振成像和超声波图像,从而获得新的成像和诊断工具。通过跟踪生物标志物,纳米结构传感器可用于发现血清肿、破裂和设备故障,而几乎不会造成任何损伤。已有许多工作表明,不同的纳米技术可以在临床前环境中帮助乳房植入物。然而,在植入物用于人体并大量生产之前,仍需解决监管和标准化方面的问题。要制造大量纳米复合材料和蚀刻表面,还需要进一步改进工艺。为了确保患者的安全,还必须进行长期的生物相容性和纳米毒理学测试。纳米技术有望改变乳房植入物的制造方式,使其更加美观,并提高人们的生活质量。本综述探讨了纳米技术在提高乳房植入物耐用性和性能方面的新兴应用。
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