Prospective cohort study of coronary vascular diseases leading to left bundle branch block and its relationship with the age after follow up of five years

Jibran Ikram, Khuram Khan, Aimen James, Eemaz Nathaniel, Ayesha Zahid, Muhammad Awais Khan, Furqan Ul Haq, Abdul Mueed Bangash, Salah Uddin, Moeen Ikram, Marium Asif, Qazi M Farooq Wahab, Muhammad Awais
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Abstract

Background: Left bundle branch block (LBBB) may be due to conduction system degeneration or in the background of myocardial infarction. It can be due to aortic valve disease Myocardial disease may be reflected in the left bundle branch block, or it may be the result of conduction system degeneration. It may also develop due to heart surgery or aortic valve dysfunction, left bundle branch block may occur. Introduction: It is due to a defect in the conduction system of left bundle branch leading to delay or blockade of along the pathway that electrical impulses travel to make the ventricles to beat. Aims and objectives · To find out the percentage of people developing LBBB. · To find out the relationship of age and coronary artery disease leading to LBBB. · To find out the survival of LBBB in various age groups. Methodology: We obtained the data of 294 patients from Rahman Hospital using a questionnaire and evaluated it using SPSS software. The data was gathered according to inclusion and exclusion criteria that determined whether a major cardiac condition like CAD was present or not. Subsequently, SPSS conducted an analysis of the data and determination was drawn. Results and Conclusion: Patients identified and studied were 297 and followed for 5 years, the study revealed that 14 percent of patients had age less than 29, 21.4 % of patients having LBBB were around age 30 to 40 years, 26.9% people of CVD had LBBB aged 50-60 years and people above 60 years having CVD had 32.2% LBBB showing that with increase in age of patient having CVD there is more risk of developing LBBB significantly. The LBBB being carrying poor prognosis, the patients were followed for 5 years, revealed that 40 out of 297 (13%) lived for 6 months, 72 out of 297 (25%) lived for 1 year approximately, 44 out of 297 (15%) lived for more than 2 years, approximately 78 out of 297 lost to follow up or died from another cause shown in the graph, which explains that approximately half of patient dies in the first 6 months of diagnosis, so this has to be taken serious and treated adequately. This research gives us a thorough foundation for comprehending how age and cardiac anomalies interact, allowing for early risk assessment of individuals and a decrease in the disease-to-ratio ratio. This initiative helps us lower risk factors, enhance the local health system, and improve patient lives by promoting routine monitoring.
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冠状血管疾病导致左束支传导阻滞及其与年龄关系的前瞻性队列研究(随访五年后
背景:左束支传导阻滞(LBBB)可能是由于传导系统退化或心肌梗死所致。左束支传导阻滞可能是由于传导系统变性或心肌梗死引起的,也可能是由于主动脉瓣疾病引起的。心脏手术或主动脉瓣功能障碍也可能导致左束支传导阻滞。简介:左束支传导阻滞左束支传导阻滞是由于左束支传导系统的缺陷导致电脉冲沿心室搏动的路径延迟或阻滞。目的和目标 - 找出发生左束支传导阻滞的人群比例。- 找出导致 LBBB 的年龄与冠状动脉疾病的关系。- 了解不同年龄组 LBBB 的存活率。研究方法我们通过问卷调查从拉赫曼医院获得了294名患者的数据,并使用SPSS软件进行了评估。这些数据是根据纳入和排除标准收集的,这些标准决定了患者是否患有主要的心脏疾病,如 CAD。随后,SPSS 对数据进行分析并得出结论。结果与结论研究显示,14%的患者年龄小于 29 岁,21.4%的 LBBB 患者年龄在 30 至 40 岁之间,26.9%的心血管疾病患者的 LBBB 年龄在 50 至 60 岁之间,60 岁以上的心血管疾病患者有 32.2% 的 LBBB。对预后不良的 LBBB 患者进行了为期 5 年的随访,结果显示,297 名患者中有 40 人(13%)存活了 6 个月,297 名患者中有 72 人(25%)存活了约 1 年,297 名患者中有 44 人(15%)存活了 2 年以上,297 名患者中有 78 人失去了随访机会或死于其他原因,如图所示,这说明约有一半的患者在确诊后的头 6 个月内死亡,因此必须认真对待并给予适当治疗。这项研究为我们了解年龄与心脏异常之间的相互影响奠定了坚实的基础,使我们能够对个人进行早期风险评估,降低疾病比例。这一举措有助于我们降低风险因素,加强当地的卫生系统,并通过促进常规监测来改善患者的生活。
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