Exploring herbal synergies: the efficacy of Pergularia daemia and co-herbs in reducing pain, swelling and inflammation

Abstract

The growing interest in herbal formulations is due to chronic illnesses, concerns about synthetic medications' safety, and the importance of natural health approaches. Herbal formulations offer a natural, affordable, and accessible therapy option with better tolerability and fewer side effects. The purpose of this study was to develop and evaluate the possible anti-inflammatory and pain relief and swelling reduction properties of herbal lep powders made from Pergularia daemia, red ochre, Boswellia Serrata, camphor, Albizia lebbeck, and mango ginger. These plants were chosen for their ethnomedical applications because to their documented swelling reduction, pain relief and anti-inflammatory qualities. The different botanicals were ground into fine powders and blended in the proper ratios to create the herbal lep powders. To evaluate the powders' bulk density, flow characteristics, and particle size distribution, physicochemical characterisation was carried out. In addition, a qualitative examination of the powders' color, texture, and Odor was done. The physicochemical parameters of the prepared herbal lep powders were found to be good, suggesting their appropriateness for topical administration. The powders also exhibited favourable organoleptic properties, which increased their acceptability for application. Although this study did not include clinical or preclinical studies, its results set the stage for future investigations into the therapeutic efficacy and safety of herbal lep powders in the treatment of pain and inflammation. In general, the process of creating and assessing these herbal lep powders shows promise in the field of creating natural treatments for inflammatory ailments.