Diagnostic utility of routine chest radiography in the evaluation of febrile neutropenia in children with cancer

Toshiba Rahman, Razia Sultana, Afroza Sultana, Habiba Khatun, Ajanta Rani Saha, M. S. Rahman
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Abstract

Background: Evaluation of febrile episodes in children who have become neutropenic during treatment for malignant disease has traditionally included in this study through screening tests for foci of infection and chest radiography. This study aimed to find out the diagnostic utility of routine chest radiography in the evaluation of febrile neutropenic in cancer children. Methods: This cross-sectional observational study was carried out in Department of Pediatrics, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh, between January 2012 to September 2012. Total 60 patients, age 6-months to 15 years included in this study. 30 cases are febrile neutropenic and 30 patients are febrile non-neutropenic. Results: All children had fever in both groups. Rales found 43.3% and 16.7% in group I and group II respectively. In group I majority (43.3%) patients had consolidation on CXR and in group II all patients had pleural effusion on CXR. Rhonchi observed 36.0% and 16.7% in group I and group II respectively. Cyanosis found only in group I, which was 16.0%. Pharygitis and pleural rub was not found in both groups. The average no of children was found 1.57±0.63 in group I and 2.0±0.83 in group II. The difference was statistically significant (p<0.05) between two groups. Conclusions: Most of the patients were ≤5 years age in both groups and male to female ratio was 1:1 in both groups.  
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常规胸片在评估癌症患儿发热性中性粒细胞减少症中的诊断作用
背景:在恶性疾病治疗过程中出现中性粒细胞减少的儿童的发热评估,传统上是通过感染灶筛查和胸部X光检查来进行的。本研究旨在了解常规胸片在评估癌症儿童发热性中性粒细胞减少症中的诊断作用:这项横断面观察性研究于 2012 年 1 月至 2012 年 9 月在孟加拉国达卡班加班杜谢赫-穆吉布医科大学儿科系进行。共有 60 名年龄在 6 个月至 15 岁之间的患者参与了这项研究。30例为发热性中性粒细胞减少症患者,30例为发热性非中性粒细胞减少症患者:两组患儿均有发热。第一组和第二组分别有 43.3% 和 16.7% 的患儿出现啰音。在第一组中,大多数(43.3%)患者的胸片有合并症,而在第二组中,所有患者的胸片都有胸腔积液。第一组和第二组分别有 36.0% 和 16.7% 的患者出现红肿。只有第一组发现了发绀,占 16.0%。两组均未发现咽喉炎和胸膜摩擦症。第一组患儿的平均人数为(1.57±0.63)人,第二组为(2.0±0.83)人。两组差异有统计学意义(P<0.05):结论:两组患者的年龄大多小于 5 岁,男女比例为 1:1。
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