Studies toward the synthesis of Colletotrichamide A: Construction of C19-C30 Segment of the Molecule

IF 1.7 4区 化学 Q3 CHEMISTRY, ORGANIC Synlett Pub Date : 2024-07-25 DOI:10.1055/a-2373-0372
Nemilikonda Sravan Kumar, Radhakrishna Gattu, B. J. Ramulu, Subhash Ghosh
{"title":"Studies toward the synthesis of Colletotrichamide A: Construction of C19-C30 Segment of the Molecule","authors":"Nemilikonda Sravan Kumar, Radhakrishna Gattu, B. J. Ramulu, Subhash Ghosh","doi":"10.1055/a-2373-0372","DOIUrl":null,"url":null,"abstract":"The synthesis of C19–C30 segment of the neuroprotective natural product colletotrichamide A has been achieved by performing Sonogashira coupling between the fragments 9 and 10. Maruoka-Keck allylation, Evans syn-aldol and Takai olefinations were used as the key steps for fragment 9 whereas glycosidation and Ohira-Bestmann reactions were used as the pivotal steps for accessing fragment 10.","PeriodicalId":22319,"journal":{"name":"Synlett","volume":null,"pages":null},"PeriodicalIF":1.7000,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Synlett","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1055/a-2373-0372","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0

Abstract

The synthesis of C19–C30 segment of the neuroprotective natural product colletotrichamide A has been achieved by performing Sonogashira coupling between the fragments 9 and 10. Maruoka-Keck allylation, Evans syn-aldol and Takai olefinations were used as the key steps for fragment 9 whereas glycosidation and Ohira-Bestmann reactions were used as the pivotal steps for accessing fragment 10.

Abstract Image

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
关于合成可乐丽酰胺 A 的研究:构建分子的 C19-C30 段
通过在片段 9 和 10 之间进行 Sonogashira 偶联,合成了具有神经保护作用的天然产物可乐三色酰胺 A 的 C19-C30 片段。片段 9 的关键步骤是 Maruoka-Keck烯丙基化反应、Evans syn-aldol 反应和 Takai 烯化反应,而片段 10 的关键步骤是糖苷化反应和 Ohira-Bestmann 反应。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Synlett
Synlett 化学-有机化学
CiteScore
3.40
自引率
5.00%
发文量
369
审稿时长
1 months
期刊介绍: SYNLETT is an international journal reporting research results and current trends in chemical synthesis in short personalized reviews and preliminary communications. It covers all fields of scientific endeavor that involve organic synthesis, including catalysis, organometallic, medicinal, biological, and photochemistry, but also related disciplines and offers the possibility to publish scientific primary data.
期刊最新文献
Skeletal Reorganization: Approaches towards the Synthesis of Aza-Heterocyclic Cores Synthesis of Phosphorodiamidate Morpholino Oligonucleotides (PMOs) Using Staudinger Reduction as a Deblocking Condition and Its Usefulness for Orthogonal Conjugation in Bi- and Trifunctionalized PMOs Sequential Copper-Catalyzed Amidation and Hydroxylation for Acetaminophen Synthesis Design and Synthesis of Out/Out, Out/In, and In/In Epoxides in Polycyclic Cage Frameworks Design of Molecular Diversity by Olefin Metathesis in Tandem with Other Reactions
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1