Blood pressure targets for the treatment of people with hypertension and cardiovascular disease

Abstract

Hypertension is a leading cause of early morbidity and mortality that can be avoided. People with hypertension and established cardiovascular disease are especially vulnerable; therefore lowering blood pressure below recommended levels could be beneficial. This technique has the potential to reduce cardiovascular mortality and morbidity, but it also has the potential to increase adverse events. In persons with hypertension and established cardiovascular disease, the ideal blood pressure target is uncertain. To see if 'lower' blood pressure targets (135 mmHg/85 mmHg) in the treatment of people with hypertension and a history of cardiovascular disease are associated with lower mortality and morbidity than' standard' blood pressure targets (140 mmHg to 160 mmHg/90 mmHg to 100 mmHg) in the treatment of people with hypertension and a history of cardiovascular disease (myocardial infarction, angina, stroke, peripheral vascular occlusive disease). High blood pressure is common in persons who have heart or vascular disorders. In those with a history of cardiac or vascular problems, certain clinical guidelines propose a lower blood pressure goal (135 mmHg/85 mmHg or lower) than in those without (normal blood pressure goals are 140 mmHg to 160 mmHg systolic and 90 mmHg to 100 mmHg diastolic). It's uncertain whether the reduced targets result in improved overall health