Worse postoperative outcomes and higher reoperation in smokers compared to nonsmokers for arthroscopic rotator cuff repair

Michael A. Gaudiani, Joshua P. Castle, Eric X Jiang, Susan G. Wager, Spencer R Brown, Johnny K Kasto, Matthew A. Gasparro, Alexander S Jurayj, E. Makhni, Vasilios Moutzouros, Stephanie J. Muh
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Abstract

This study aimed to determine if smokers at the time of arthroscopic rotator cuff repair met the minimally clinical important difference and substantial clinical benefit for Patient-Reported Outcomes Measurement Information System Upper Extremity, Depression, and Pain Interference scores in comparison to nonsmoking patients in a retrospective review. Clinical outcomes and Patient-Reported Outcomes Measurement Information System scores were compared between a cohort of nonsmokers and current or former smokers (smokers). Further sub-analysis compared a cohort of nonsmokers propensity-matched 1:1 to a cohort of current/former smokers via age, body mass index, and tear size. A total of 182 patients, 80 smokers and 102 nonsmokers, were included. Smokers had statistically different-sized tears with more rated massive ( P = 0.02) and more reoperations ( P = 0.02). Smokers met substantial clinical benefit thresholds at a lower rate than nonsmokers for Patient-Reported Outcomes Measurement Information System Upper Extremity ( P = 0.03). In the sub-analysis, 74 smokers were matched to 74 nonsmokers. Smokers had a lower change in Patient-Reported Outcomes Measurement Information System Upper Extremity ( P = 0.007) and Patient-Reported Outcomes Measurement Information System Pain Interference ( P = 0.03) postoperatively. Fewer smokers met minimally clinical important difference for Patient-Reported Outcomes Measurement Information System Upper Extremity postoperatively ( P = 0.003) and more had reoperations ( P = 0.02). Overall, smokers demonstrated smaller improvements in function, and pain, and were less likely to meet minimally clinical important differences and substantial clinical benefits for Patient-Reported Outcomes Measurement Information System Upper Extremity at 6 months follow-up when compared to nonsmokers after rotator cuff repair.
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与非吸烟者相比,吸烟者接受关节镜肩袖修复术的术后效果更差,再次手术率更高
本研究旨在通过一项回顾性研究,确定在进行关节镜肩袖修复术时吸烟者与不吸烟患者相比,在患者报告结果测量信息系统(Patient-Reported Outcomes Measurement Information System)上肢、抑郁和疼痛干扰评分方面是否达到了最小临床重要差异和实质性临床获益。临床结果和患者报告结果测量信息系统评分在不吸烟者和目前或曾经吸烟者(吸烟者)之间进行了比较。进一步的子分析通过年龄、体重指数和泪液大小,将倾向匹配为 1:1 的非吸烟者队列与当前/曾经吸烟者队列进行了比较。共纳入了 182 名患者,其中 80 人为吸烟者,102 人为非吸烟者。从统计学角度看,吸烟者的撕裂大小不同,大面积撕裂的比例更高(P = 0.02),再次手术的比例更高(P = 0.02)。在 "患者报告结果测量信息系统"(Patient-Reported Outcomes Measurement Information System Upper Extremity)中,吸烟者达到实质性临床获益阈值的比例低于非吸烟者(P = 0.03)。在子分析中,74 名吸烟者与 74 名非吸烟者进行了配对。吸烟者术后在 "患者报告结果测量信息系统上肢"(P = 0.007)和 "患者报告结果测量信息系统疼痛干扰"(P = 0.03)方面的变化较小。术后达到 "患者报告结果测量信息系统"(Patient-Reported Outcomes Measurement Information System)上肢最小临床意义差异的吸烟者较少(P = 0.003),再次手术的吸烟者较多(P = 0.02)。总体而言,与肩袖修复术后不吸烟者相比,吸烟者在功能和疼痛方面的改善较小,在随访6个月时达到 "患者报告结果测量信息系统上肢 "最小临床意义差异和实质性临床获益的可能性较小。
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