Antidiabetic drugs as the future of obesity treatment

Abstract

Obesity is a multifactorial chronic disease with complex pathogenesis. Its causes are considered to be genetic, biological, epigenetic, environmental, developmental and behavioral factors leading to excessive caloric intake and, consequently, weight gain. As body weight increases, the risk of developing many chronic diseases increases and, as a result, life expectancy decreases. The basis of obesity treatment is the introduction of changes in behavior and lifestyle modification, based primarily on the adoption of a healthy, balanced diet with a caloric deficit, regular physical activity and limiting sedentary time. If they are ineffective, pharmacological methods are considered and, if necessary, surgical procedures are performed. Nowadays, more and more attention is paid to obesity as a multifactorial disease that must be effectively treated. It is not only an aesthetic problem but also a serious disease that can lead to premature death. Our work focuses on a review of current methods in the treatment of obesity, with particular attention to the latest pharmacological methods.