{"title":"The Potential of Crocus sativus in the treatment of Burns—mini Review","authors":"Fatima R.Abd-alwahid, Marwa L.Jabur, Lubna A.Mohammed","doi":"10.55640/ijmsdh-10-07-03","DOIUrl":null,"url":null,"abstract":"This article under review summarizes clinical and animal model studies that prove the potential of ingredients of saffron including safranal, crocetin and crocins extracts and their admixtures in treating of burn wound because of treating of burns still a receive attention in contemporary medicine, notably in developing nations that cannot supply costly and progressive medicines.Reviews presented in databases such as Google Scholar,Scopus,Pub-Med,Web of Science and Science Direct, published in English in 2008–2022,were considered.According to medical trials which described, it was shown that saffran extracts have notable effectiveness in treating of burn wounds, including reducing inflammation and speeding up the healing process than the conventional treatment used hitherto. This current review emphasis on the aspect of the main active comounds of saffron, on healing burn and the mechanisms investigated by researchers in treating. Researches on animal pattern indications that saffran preparation may have potential beneficial in the treatment burn wounds.According to antibacterial activity,mechanism of action, low toxicity and mild cost, saffran extracts can compete with conventional treatment.","PeriodicalId":503011,"journal":{"name":"International Journal of Medical Science and Dental Health","volume":" 2","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Medical Science and Dental Health","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.55640/ijmsdh-10-07-03","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
This article under review summarizes clinical and animal model studies that prove the potential of ingredients of saffron including safranal, crocetin and crocins extracts and their admixtures in treating of burn wound because of treating of burns still a receive attention in contemporary medicine, notably in developing nations that cannot supply costly and progressive medicines.Reviews presented in databases such as Google Scholar,Scopus,Pub-Med,Web of Science and Science Direct, published in English in 2008–2022,were considered.According to medical trials which described, it was shown that saffran extracts have notable effectiveness in treating of burn wounds, including reducing inflammation and speeding up the healing process than the conventional treatment used hitherto. This current review emphasis on the aspect of the main active comounds of saffron, on healing burn and the mechanisms investigated by researchers in treating. Researches on animal pattern indications that saffran preparation may have potential beneficial in the treatment burn wounds.According to antibacterial activity,mechanism of action, low toxicity and mild cost, saffran extracts can compete with conventional treatment.
本文综述了一些临床和动物模型研究,这些研究证明了藏红花成分(包括藏红花醛、藏红花素和藏红花甙提取物及其混合物)在治疗烧伤创面方面的潜力,因为烧伤治疗仍然受到当代医学的关注,尤其是在无法提供昂贵和先进药物的发展中国家。本综述考虑了谷歌学者、Scopus、Pub-Med、Web of Science 和 Science Direct 等数据库中 2008-2022 年发表的英文综述。根据医学试验的描述,红景天提取物在治疗烧伤创面方面具有显著效果,包括与迄今为止使用的传统治疗方法相比,可减少炎症反应并加快愈合过程。本综述的重点是藏红花的主要活性化合物对烧伤愈合的作用,以及研究人员对其治疗机制的调查。对动物模式的研究表明,藏红花制剂可能对治疗烧伤伤口有潜在的益处。根据抗菌活性、作用机制、低毒性和低成本,藏红花提取物可以与传统疗法相抗衡。