Critical Management of Recurrent Seizure at 16-Year-Old Primigravida with Atypical Eclampsia: A Case Report

Putu Ari, HS Kamanjaya, Febri Jaya, Gunawan
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Abstract

Background: Atypical eclampsia, characterized by seizures without the classic signs of hypertension and proteinuria, presents a diagnostic and therapeutic challenge in the critical management aspect. This case report highlights the critical management of recurrent seizures in a young primigravida with atypical eclampsia. Case presentation: A 16-year-old primigravida at 38 weeks gestation presented with recurrent generalized tonic-clonic seizures. Despite initial magnesium sulfate therapy, seizures persisted postpartum. The patient was managed with a combination of midazolam and dexmedetomidine for seizure control and sedation. After five days of intensive care, the patient recovered without further complications. Conclusion: This case underscores the importance of considering atypical eclampsia in pregnant women presenting with seizures, even in the absence of typical preeclampsia symptoms. The successful use of midazolam and dexmedetomidine in this case suggests their potential as alternative therapeutic agents for refractory seizures in eclampsia. Further research is needed to validate these findings and establish optimal treatment protocols for atypical eclampsia.
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16 岁初产妇非典型子痫反复发作的关键处理:病例报告
背景:非典型子痫的特点是癫痫发作,但无高血压和蛋白尿等典型体征,这给危重症的诊断和治疗带来了挑战。本病例报告重点介绍了一名患有非典型子痫的年轻初产妇反复癫痫发作的关键处理方法。病例介绍:一名妊娠 38 周的 16 岁初产妇反复出现全身强直阵挛发作。尽管最初使用了硫酸镁治疗,但产后癫痫仍持续发作。患者接受了咪达唑仑和右美托咪定联合治疗,以控制癫痫发作和镇静。经过五天的重症监护,患者康复,未再出现并发症。结论本病例强调了在孕妇出现癫痫发作时,即使没有典型的子痫前期症状,也要考虑非典型子痫的重要性。在本病例中成功使用咪达唑仑和右美托咪定表明,它们有可能成为子痫难治性癫痫发作的替代治疗药物。还需要进一步研究来验证这些发现,并为非典型子痫制定最佳治疗方案。
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