Development of a New Prototype Paediatric Central Sleep Apnoea Monitor

Reza Saatchi, Heather Elphick, Jennifer Rowson, Mark Wesseler, Jacob Marris, Sarah Shortland, Lowri Thomas
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Abstract

A new prototype device to monitor breathing in children diagnosed with central sleep apnoea (CSA) was developed. CSA is caused by the failure of central nervous system signals to the respiratory muscles and results in intermittent breathing pauses during sleep. Children diagnosed with CSA require home respiration monitoring during sleep. Apnoea monitors initiate an audio alarm when the breath-to-breath respiration interval exceeds a preset time. This allows the child’s parents to attend to the child to ensure safety. The article describes the development of the monitor’s hardware, software, and evaluation. Features of the device include the detection of abnormal respiratory pauses and the generation of an associated alarm, the ability to record the respiratory signal and its storage using an on-board disk, miniaturised hardware, child-friendliness, cost-effectiveness, and ease of use. The device was evaluated on 10 healthy adult volunteers with a mean age of 46.6 years (and a standard deviation of 14.4 years). The participants randomly intentionally paused their breathing during the recording. The device detected and provided an alarm when the respiratory pauses exceeded the preset time. The respiration rates determined from the device closely matched the values from a commercial respiration monitor. The study indicated the peak-detection method of the respiration rate measurement is more robust than the zero-crossing method.
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开发新型儿科中央睡眠呼吸监测仪原型
我们开发了一种新的原型设备,用于监测被诊断患有中枢性睡眠呼吸暂停(CSA)的儿童的呼吸情况。中枢性睡眠呼吸暂停是由于中枢神经系统向呼吸肌发出的信号失灵,导致睡眠时呼吸间歇性暂停。被诊断为 CSA 的儿童需要在睡眠期间接受家庭呼吸监测。呼吸暂停监测仪会在呼吸间隔超过预设时间时发出声音警报。这样,孩子的父母就可以照看孩子,确保安全。文章介绍了监测器硬件、软件的开发和评估。该设备的特点包括检测异常呼吸暂停并发出相关警报、记录呼吸信号并使用板载磁盘存储、硬件微型化、儿童友好性、成本效益和易用性。该设备在 10 名平均年龄为 46.6 岁(标准差为 14.4 岁)的健康成年志愿者身上进行了评估。在记录过程中,参与者随机故意暂停呼吸。当呼吸暂停超过预设时间时,设备会检测到并发出警报。该装置测定的呼吸频率与商用呼吸监测仪的数值非常吻合。研究表明,呼吸频率测量的峰值检测法比零点交叉法更稳健。
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