First person – Ke Shan and Trieu Le

Abstract

First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping researchers promote themselves alongside their papers. Ke Shan and Trieu Le are co-first authors on ‘ TMEM16F scramblase regulates angiogenesis via endothelial intracellular signaling’, published in JCS. Ke is a PhD candidate in the lab of Huanghe Yang at Duke University, School of Medicine, Durham, USA, investigating how TMEM16F scramblase-mediated collapse of phospholipid asymmetry controls biological functions, including blood coagulation, vessel formation and mechanical responses. Trieu performed this work while in the same laboratory and is now a postdoctoral fellow in the lab of Dr Sergio Grinstein and Dr Spencer for the Program in Cell Biology, Hospital for Sick Children, Toronto, Canada, investigating how the spatial organization of lipids, proteins, and macromolecules on the surface of cells contributes to cancer cells' evasion from immune surveillance.