Mucoepidermoid carcinoma arising in salivary hyperplasia of the hard palate in a pediatric patient

IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2025-03-01 Epub Date: 2024-07-25 DOI:10.1016/j.ajoms.2024.07.006
Eri Yumoto , Ryo Kajihara , Yuki Sakai , Shin-ichi Yamada , Takeshi Koike , Hiroshi Kurita
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Abstract

Primary malignant salivary gland tumors are rare among pediatric patients. There are few reports about mucoepidermoid carcinoma (MEC) in the minor salivary gland in pediatric patients. Herein, we report a case of MEC that arose in salivary hyperplasia on the hard palate in a 10-year-old girl. A 10-year-old girl presented with swelling on the left side of the hard palate. She was referred to our department in October 202X. The patient had experienced swelling of the left hard palate for 2 years, which had been slowly increasing in size. Upon examination, a single, dome-shaped, well-defined mass measuring 18 × 12 mm was observed. Mucosa was normal and there was no tenderness on the left hard palate. The mass showed low signal intensity on T2-weighted magnetic resonance imaging. A biopsy was performed. Although the result indicated salivary hyperplasia, due to suspicion of tumor, total resection was performed. We resected the mass along with the periosteum and removed one layer of the palatal bone under general anesthesia. Histopathologic examination of the surgical specimen revealed low-grade mucoepidermoid carcinoma. We performed careful follow-up. There was no evidence of recurrence as of 2 years post-surgery.
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一名儿童患者硬腭唾液腺增生引发的黏液表皮样癌
原发性唾液腺恶性肿瘤在儿科患者中是罕见的。关于小儿小涎腺粘液表皮样癌(MEC)的报道很少。在此,我们报告一例MEC,出现在一个10岁的女孩在硬腭的唾液增生。一个十岁的女孩表现为左侧硬腭肿胀。她于2012年10月被转介到我们部门。患者左侧硬腭肿胀2年,并逐渐增大。检查后,观察到一个单一的,圆顶状的,明确的质量,尺寸为18 × 12 mm。左硬腭粘膜正常,无压痛。肿块在t2加权磁共振成像上显示低信号强度。进行了活检。结果虽为涎腺增生,但因怀疑为肿瘤,仍行全切除。我们在全身麻醉下切除肿块和骨膜,并切除一层腭骨。手术标本的组织病理学检查显示为低级别粘液表皮样癌。我们进行了仔细的随访。术后2年无复发迹象。
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来源期刊
CiteScore
0.80
自引率
0.00%
发文量
129
审稿时长
83 days
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