Perioperative management of patients with postoperative nausea and vomiting (PONV) risks

IF 0.2 Q4 ANESTHESIOLOGY Anaesthesia and Intensive Care Medicine Pub Date : 2024-08-01 DOI:10.1016/j.mpaic.2024.07.011

Jonathan Pang, Alfred Chan

引用次数: 0

Abstract

Postoperative nausea and vomiting (PONV) is a common distressing symptom for patients undergoing surgery and anaesthesia, with incidence ranging from 30% in the general population up to 80% in the high-risk cohort. PONV increases patient dissatisfaction, with additional surgical and anaesthetic implications such as aspiration, wound dehiscence and raised intracranial pressure

This article highlights multifactorial aetiologies of PONV including patient, anaesthetic and surgical related factors. Neuropharmacology including activation of various receptors (dopaminergic, muscarinic, serotonergic) and cranial nerves VIII (acoustic-vestibular), IX (glossopharyngeal) and X (vagus nerve) is discussed. The most up-to-date PONV management and novel therapies are also discussed after literature review.

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对有术后恶心和呕吐（PONV）风险的患者进行围手术期管理

术后恶心和呕吐（PONV）是接受手术和麻醉的患者常见的痛苦症状，发生率从普通人群的 30% 到高危人群的 80%。PONV 会增加患者的不满情绪，并对手术和麻醉产生额外的影响，如吸入、伤口裂开和颅内压升高。文章讨论了神经药理学，包括各种受体（多巴胺能、毒蕈碱能、血清素能）和颅神经 VIII（听觉前庭神经）、IX（舌咽神经）和 X（迷走神经）的激活。文献综述后还讨论了最新的 PONV 处理方法和新型疗法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Anaesthesia and Intensive Care Medicine ANESTHESIOLOGY-

CiteScore

0.50

自引率

0.00%

发文量

152

期刊介绍： Anaesthesia and Intensive Care Medicine, an invaluable source of up-to-date information, with the curriculum of both the Primary and Final FRCA examinations covered over a three-year cycle. Published monthly this ever-updating text book will be an invaluable source for both trainee and experienced anaesthetists. The enthusiastic editorial board, under the guidance of two eminent and experienced series editors, ensures Anaesthesia and Intensive Care Medicine covers all the key topics in a comprehensive and authoritative manner. Articles now include learning objectives and eash issue features MCQs, facilitating self-directed learning and enabling readers at all levels to test their knowledge. Each issue is divided between basic scientific and clinical sections. The basic science articles include anatomy, physiology, pharmacology, physics and clinical measurement, while the clinical sections cover anaesthetic agents and techniques, assessment and perioperative management. Further sections cover audit, trials, statistics, ethical and legal medicine, and the management of acute and chronic pain.

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