Acute kidney injury in hospitalized children in 20 hospitals of China's Hunan Province: a cross-sectional survey.

IF 3 3区医学 Q1 UROLOGY & NEPHROLOGY Renal Failure Pub Date : 2024-12-01 Epub Date: 2024-07-31 DOI:10.1080/0886022X.2024.2379003

Qianliang Sun, Ying Pan, Zhihui Li

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Abstract

Objective: The incidence of acute kidney injury (AKI) in pediatric patients has been increasing over the years, and AKI significantly impacts children's health and quality of life. This article reviews the current epidemiological research on pediatric AKI.

Methods: The clinical data of hospitalized children aged 0 to 14 years from 20 different hospitals in Hunan Province, China, collected from December 2017 to February 2018, were analyzed. The incidence rate, misdiagnosis rate, main causes, and medical costs of AKI in hospitalized children were examined.

Results: A total of 29,639 patients were included, with an AKI incidence rate of 4.34% (1286/29,639). Among the 1286 AKI patients, 863 (67.11%) were classified as AKI stage 1324 (25.19%) as AKI stage 2, and 99 (7.7%) as AKI stage 3. AKI patients had significantly longer hospital stays [6.0 (4.0, 10) days vs. 6.0 (4.0, 8.0) days, p < 0.001] and higher hospitalization costs [3375.22 (1600, 6083.83) yuan vs. 2729.4 (1659.45, 8216.65) yuan, p = 0.003] than non-AKI patients. The mortality rate (1.2% vs. 0.1%, p < 0.001), intensive care unit (ICU) transfer rate (8.7% vs. 5.97%, p < 0.001), and use of invasive mechanical ventilation (3.6% vs. 1%, p < 0.001) were significantly greater in patients with AKI than in those without AKI patients. The etiology of AKI varied among different age groups, and dehydration, diarrhea, and shock were the main causes of pre-renal AKI.

Conclusion: The incidence and missed diagnosis rates of AKI in hospitalized children were high. AKI prolongs hospital stays, increases hospitalization costs, and increases the risk of mortality in children.

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中国湖南省 20 家医院住院儿童急性肾损伤横断面调查。

目的：近年来，小儿急性肾损伤（AKI）的发病率不断上升，AKI严重影响了儿童的健康和生活质量。本文回顾了目前关于儿科 AKI 的流行病学研究：分析了2017年12月至2018年2月收集的中国湖南省20家不同医院0至14岁住院儿童的临床数据。研究住院患儿AKI的发病率、误诊率、主要病因、医疗费用等：共纳入29639名患者，AKI发病率为4.34%（1286/29639）。在 1286 例 AKI 患者中，863 例（67.11%）被划分为 AKI 阶段，1324 例（25.19%）被划分为 AKI 阶段 2，99 例（7.7%）被划分为 AKI 阶段 3。与非 AKI 患者相比，AKI 患者的住院时间明显更长 [6.0 (4.0, 10) 天 vs. 6.0 (4.0, 8.0) 天，P = 0.003]。死亡率（1.2% 对 0.1%，P=0.003）：住院儿童的 AKI 发生率和漏诊率都很高。AKI 会延长住院时间，增加住院费用，并增加儿童的死亡风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Renal Failure 医学-泌尿学与肾脏学

CiteScore

3.90

自引率

13.30%

发文量

374

审稿时长

1 months

期刊介绍： Renal Failure primarily concentrates on acute renal injury and its consequence, but also addresses advances in the fields of chronic renal failure, hypertension, and renal transplantation. Bringing together both clinical and experimental aspects of renal failure, this publication presents timely, practical information on pathology and pathophysiology of acute renal failure; nephrotoxicity of drugs and other substances; prevention, treatment, and therapy of renal failure; renal failure in association with transplantation, hypertension, and diabetes mellitus.