Pregnancy in Autoimmune Hypophysitis: Management of a Rare Condition.

Flavia Costanza, Martina Cicia, Antonella Giampietro, Tommaso Tartaglione, Flavia Angelini, Angelo Zoli, Sergio Ferrazzani, Laura De Marinis, Alfredo Pontecorvi, Antonio Bianchi, Sabrina Chiloiro
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Abstract

Introduction: Hypophysitis is an inflammatory disorder of the pituitary gland. It can manifest variously, with endocrinological and neuro-ophthalmologic symptoms and signs, due to the compression of sellar and parasellar structures.

Case representation: Although hypophysitis is rare, this pituitary disease can occur during pregnancy or in the postpartum period. In this report, we describe the case of a woman with partial hypopituitarism secondary to autoimmune hypophysitis who, five years after the diagnosis and the immunosuppressive treatment, had an uneventful pregnancy and successfully delivered a healthy infant at term.

Conclusion: We reported the clinical history of the patient and the evolution of the disease and also reviewed the management and treatment of autoimmune hypophysitis during pregnancy.

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自身免疫性肾上腺皮质功能减退症患者的妊娠:罕见病症的处理。
简介垂体炎是垂体的一种炎症性疾病。由于压迫蝶鞍和蝶鞍旁结构,它可以表现出不同的内分泌和神经眼科症状和体征:虽然垂体功能减退症很少见,但这种垂体疾病可发生在妊娠期或产后。在本报告中,我们描述了一例继发于自身免疫性垂体功能减退症的部分垂体功能减退症女性患者,在确诊并接受免疫抑制治疗五年后,她顺利怀孕并成功分娩了一名足月健康婴儿:我们报告了患者的临床病史和疾病的演变过程,并回顾了妊娠期自身免疫性垂体功能减退症的管理和治疗。
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