Enhanced High-Resolution Compact Microscopy Based on the Fiber Optic Array and Microsphere

IF 2.3 3区 工程技术 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC IEEE Photonics Technology Letters Pub Date : 2024-07-29 DOI:10.1109/LPT.2024.3435538
Xinjie Zhang;Jibin Wei;Jing Sun;Zengrun Wen;Yangjian Cai;Weiming Wang
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Abstract

High resolution is important properties of the compact microscopy in the point-of-care testing (POCT) and management of various infectious diseases. However, the current high-resolution compact microscopy usually has complicated algorithm at the expense of real-time. This letter experimentally demonstrated a method to improve the resolution of compact microscope by employing the microsphere, in combination with the tube lens placed on the small-end of the fiber optic array (FOA) which termed MLFOA. This device achieves an impressive resolution of <430nm> $430\mu $ m $^{\mathbf {2}}$ without using any algorithm processing and film, the highest among the compact microscopes to our best knowledge. The material (refractive index, NA), the diameter, the light wavelength, immerse liquid of the microsphere is measured by using the MLFOA. The device can potentially be expandable for the point-of-care testing (POCT) detection.
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基于光纤阵列和微球的增强型高分辨率紧凑显微镜
在各种传染病的床旁检测(POCT)和管理中,高分辨率是紧凑型显微镜的重要特性。然而,目前的高分辨率紧凑型显微镜通常算法复杂,牺牲了实时性。这封信通过实验证明了一种提高紧凑型显微镜分辨率的方法,即在光纤阵列(FOA)的小端采用微球与管透镜相结合的方法,这种方法被称为 MLFOA。在不使用任何算法处理和胶片的情况下,该设备的分辨率达到了惊人的 $430\mu $ m $^{\mathbf{2}}$,是我们所知的紧凑型显微镜中最高的。使用 MLFOA 可以测量微球的材料(折射率,NA)、直径、光波长和浸入液体。该设备可扩展用于护理点检测(POCT)。
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来源期刊
IEEE Photonics Technology Letters
IEEE Photonics Technology Letters 工程技术-工程:电子与电气
CiteScore
5.00
自引率
3.80%
发文量
404
审稿时长
2.0 months
期刊介绍: IEEE Photonics Technology Letters addresses all aspects of the IEEE Photonics Society Constitutional Field of Interest with emphasis on photonic/lightwave components and applications, laser physics and systems and laser/electro-optics technology. Examples of subject areas for the above areas of concentration are integrated optic and optoelectronic devices, high-power laser arrays (e.g. diode, CO2), free electron lasers, solid, state lasers, laser materials'' interactions and femtosecond laser techniques. The letters journal publishes engineering, applied physics and physics oriented papers. Emphasis is on rapid publication of timely manuscripts. A goal is to provide a focal point of quality engineering-oriented papers in the electro-optics field not found in other rapid-publication journals.
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