Effect of adding ytterbium trifluoride filler particles on the mechanical, physicochemical and biological properties of methacrylate-based experimental resins for 3D printing

IF 4.6 1区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Dental Materials Pub Date : 2024-08-02 DOI:10.1016/j.dental.2024.07.023

Emanuela Gaviolli , Fabricio Mezzomo Collares , Gabriela de Souza Balbinot , Mutlu Özcan , Vicente Castelo Branco Leitune

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Abstract

Objective

To formulate an experimental methacrylate-based photo-polymerizable resin for 3D printing with ytterbium trifluoride as filler and to evaluate the mechanical, physicochemical, and biological properties.

Methods

Resin matrix was formulated with 60 wt% UDMA, 40 wt% TEGDMA, 1 wt% TPO, and 0.01 wt% BHT. Ytterbium Trifluoride was added in concentrations of 1 (G_1 %), 2 (G_2 %), 3 (G_3 %), 4 (G_4 %), and 5 (G_5 %) wt%. One group remained without filler addition as control (G_C). The samples were designed in 3D builder software and printed using a UV-DLP 3D printer. The samples were ultrasonicated with isopropanol and UV cured for 60 min. The resins were tested for degree of conversion (DC), flexural strength, Knoop microhardness, softening in solvent, radiopacity, colorimetric analysis, and cytotoxicity (MTT and SRB).

Results

Post-polymerization increased the degree of conversion of all groups (p < 0.05). G_2 % showed the highest DC after post-polymerization. G_2 % showed no differences in flexural strength from the G_1 % and G_C (p > 0.05). All groups showed a hardness reduction after solvent immersion. No statistical difference was found in radiopacity, softening in solvent (ΔKHN%), colorimetric spectrophotometry, and cytotoxicity (MTT) (p > 0.05). G_1 % showed reduced cell viability for SRB assay (p < 0.05).

Significance

It was possible to produce an experimental photo-polymerizable 3D printable resin with the addition of 2 % ytterbium trifluoride as filler without compromising the mechanical, physicochemical, and biological properties, comparable to the current provisional materials.

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添加三氟化镱填料颗粒对用于 3D 打印的甲基丙烯酸酯基实验树脂的机械、理化和生物特性的影响。

目的以三氟化镱为填料，配制一种用于 3D 打印的甲基丙烯酸酯基光聚合树脂，并评估其机械、理化和生物特性：树脂基体由 60 wt% UDMA、40 wt% TEGDMA、1 wt% TPO 和 0.01 wt% BHT 配制而成。三氟化镱的添加浓度分别为 1 (G1 %)、2 (G2 %)、3 (G3 %)、4 (G4 %) 和 5 (G5 %)。一组不添加填料，作为对照组（GC）。样品由 3D 生成器软件设计，并使用 UV-DLP 3D 打印机打印。用异丙醇对样品进行超声处理，然后紫外线固化 60 分钟。测试了树脂的转换度（DC）、弯曲强度、努氏显微硬度、溶剂软化、不透射线性、比色分析和细胞毒性（MTT 和 SRB）：后聚合提高了所有组的转化率（p 2 % 在后聚合后显示出最高的直流电。G2 % 与 G1 % 和 GC 的抗弯强度没有差异（p > 0.05）。所有组别在溶剂浸泡后硬度都有所下降。在放射性、溶剂软化（ΔKHN%）、色度分光光度法和细胞毒性（MTT）方面均未发现统计学差异（p > 0.05）。在 SRB 检测中，G1 % 显示细胞活力降低（p 显著性）：通过添加 2% 的三氟化镱作为填料，在不影响机械、物理化学和生物特性的情况下，生产出了一种实验性光聚合三维可打印树脂，其性能可媲美目前的临时材料。

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来源期刊

Dental Materials 工程技术-材料科学：生物材料

CiteScore

9.80

自引率

10.00%

发文量

290

审稿时长

67 days

期刊介绍： Dental Materials publishes original research, review articles, and short communications. Academy of Dental Materials members click here to register for free access to Dental Materials online. The principal aim of Dental Materials is to promote rapid communication of scientific information between academia, industry, and the dental practitioner. Original Manuscripts on clinical and laboratory research of basic and applied character which focus on the properties or performance of dental materials or the reaction of host tissues to materials are given priority publication. Other acceptable topics include application technology in clinical dentistry and dental laboratory technology. Comprehensive reviews and editorial commentaries on pertinent subjects will be considered.