Automated measurement of lumbar pedicle screw parameters using deep learning algorithm on preoperative CT scans

IF 3.4 2区 医学 Q2 Medicine Journal of Bone Oncology Pub Date : 2024-08-01 DOI:10.1016/j.jbo.2024.100627
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Abstract

Purpose

This study aims to devise and assess an automated measurement framework for lumbar pedicle screw parameters leveraging preoperative computed tomography (CT) scans and a deep learning algorithm.

Methods

A deep learning model was constructed employing a dataset comprising 1410 axial preoperative CT images of lumbar pedicles sourced from 282 patients. The model was trained to predict several screw parameters, including the axial angle and width of pedicles, the length of pedicle screw paths, and the interpedicular distance. The mean values of these parameters, as determined by two radiologists and one spinal surgeon, served as the reference standard.

Results

The deep learning model achieved high agreement with the reference standard for the axial angle of the left pedicle (ICC = 0.92) and right pedicle (ICC = 0.93), as well as for the length of the left pedicle screw path (ICC = 0.82) and right pedicle (ICC = 0.87). Similarly, high agreement was observed for pedicle width (left ICC = 0.97, right ICC = 0.98) and interpedicular distance (ICC = 0.91). Overall, the model’s performance paralleled that of manual determination of lumbar pedicle screw parameters.

Conclusion

The developed deep learning-based model demonstrates proficiency in accurately identifying landmarks on preoperative CT scans and autonomously generating parameters relevant to lumbar pedicle screw placement. These findings suggest its potential to offer efficient and precise measurements for clinical applications.

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利用深度学习算法在术前 CT 扫描上自动测量腰椎椎弓根螺钉参数
本研究旨在利用术前计算机断层扫描(CT)和深度学习算法,设计并评估腰椎椎弓根螺钉参数的自动测量框架。深度学习模型的数据集由来自 282 名患者的 1410 幅腰椎椎弓根术前轴向 CT 图像组成。对该模型进行了训练,以预测多个螺钉参数,包括椎弓根的轴向角度和宽度、椎弓根螺钉路径的长度以及关节间距离。这些参数的平均值由两名放射科医生和一名脊柱外科医生确定,作为参考标准。在左侧椎弓根轴向角度(ICC = 0.92)和右侧椎弓根轴向角度(ICC = 0.93)以及左侧椎弓根螺钉路径长度(ICC = 0.82)和右侧椎弓根长度(ICC = 0.87)方面,深度学习模型与参考标准的一致性很高。同样,椎弓根宽度(左侧 ICC = 0.97,右侧 ICC = 0.98)和关节间距离(ICC = 0.91)的一致性也很高。总体而言,该模型的性能与人工确定腰椎椎弓根螺钉参数的性能相当。所开发的基于深度学习的模型在准确识别术前 CT 扫描上的地标和自主生成腰椎椎弓根螺钉置入相关参数方面表现出了很高的能力。这些研究结果表明,该模型具有为临床应用提供高效、精确测量的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
7.20
自引率
2.90%
发文量
50
审稿时长
34 days
期刊介绍: The Journal of Bone Oncology is a peer-reviewed international journal aimed at presenting basic, translational and clinical high-quality research related to bone and cancer. As the first journal dedicated to cancer induced bone diseases, JBO welcomes original research articles, review articles, editorials and opinion pieces. Case reports will only be considered in exceptional circumstances and only when accompanied by a comprehensive review of the subject. The areas covered by the journal include: Bone metastases (pathophysiology, epidemiology, diagnostics, clinical features, prevention, treatment) Preclinical models of metastasis Bone microenvironment in cancer (stem cell, bone cell and cancer interactions) Bone targeted therapy (pharmacology, therapeutic targets, drug development, clinical trials, side-effects, outcome research, health economics) Cancer treatment induced bone loss (epidemiology, pathophysiology, prevention and management) Bone imaging (clinical and animal, skeletal interventional radiology) Bone biomarkers (clinical and translational applications) Radiotherapy and radio-isotopes Skeletal complications Bone pain (mechanisms and management) Orthopaedic cancer surgery Primary bone tumours Clinical guidelines Multidisciplinary care Keywords: bisphosphonate, bone, breast cancer, cancer, CTIBL, denosumab, metastasis, myeloma, osteoblast, osteoclast, osteooncology, osteo-oncology, prostate cancer, skeleton, tumour.
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