{"title":"Diffusion model based on generalized map for accelerated MRI.","authors":"Zengwei Xiao, Yujuan Lu, Binzhong He, Pinhuang Tan, Shanshan Wang, Xiaoling Xu, Qiegen Liu","doi":"10.1002/nbm.5232","DOIUrl":null,"url":null,"abstract":"<p><p>In recent years, diffusion models have made significant progress in accelerating magnetic resonance imaging. Nevertheless, it still has inherent limitations, such as prolonged iteration times and sluggish convergence rates. In this work, we present a novel generalized map generation model based on mean-reverting SDE, called GM-SDE, to alleviate these shortcomings. Notably, the core idea of GM-SDE is optimizing the initial values of the iterative algorithm. Specifically, the training process of GM-SDE diffuses the original k-space data to an intermediary degraded state with fixed Gaussian noise, while the reconstruction process generates the data by reversing this process. Based on the generalized map, three variants of GM-SDE are proposed to learn k-space data with different structural characteristics to improve the effectiveness of model training. GM-SDE also exhibits flexibility, as it can be integrated with traditional constraints, thereby further enhancing its overall performance. Experimental results showed that the proposed method can reduce reconstruction time and deliver excellent image reconstruction capabilities compared to the complete diffusion-based method.</p>","PeriodicalId":19309,"journal":{"name":"NMR in Biomedicine","volume":" ","pages":"e5232"},"PeriodicalIF":2.7000,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"NMR in Biomedicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/nbm.5232","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/8/4 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"BIOPHYSICS","Score":null,"Total":0}
引用次数: 0
Abstract
In recent years, diffusion models have made significant progress in accelerating magnetic resonance imaging. Nevertheless, it still has inherent limitations, such as prolonged iteration times and sluggish convergence rates. In this work, we present a novel generalized map generation model based on mean-reverting SDE, called GM-SDE, to alleviate these shortcomings. Notably, the core idea of GM-SDE is optimizing the initial values of the iterative algorithm. Specifically, the training process of GM-SDE diffuses the original k-space data to an intermediary degraded state with fixed Gaussian noise, while the reconstruction process generates the data by reversing this process. Based on the generalized map, three variants of GM-SDE are proposed to learn k-space data with different structural characteristics to improve the effectiveness of model training. GM-SDE also exhibits flexibility, as it can be integrated with traditional constraints, thereby further enhancing its overall performance. Experimental results showed that the proposed method can reduce reconstruction time and deliver excellent image reconstruction capabilities compared to the complete diffusion-based method.
期刊介绍:
NMR in Biomedicine is a journal devoted to the publication of original full-length papers, rapid communications and review articles describing the development of magnetic resonance spectroscopy or imaging methods or their use to investigate physiological, biochemical, biophysical or medical problems. Topics for submitted papers should be in one of the following general categories: (a) development of methods and instrumentation for MR of biological systems; (b) studies of normal or diseased organs, tissues or cells; (c) diagnosis or treatment of disease. Reports may cover work on patients or healthy human subjects, in vivo animal experiments, studies of isolated organs or cultured cells, analysis of tissue extracts, NMR theory, experimental techniques, or instrumentation.