Diffusion model based on generalized map for accelerated MRI.

IF 2.7 4区 医学 Q2 BIOPHYSICS NMR in Biomedicine Pub Date : 2024-12-01 Epub Date: 2024-08-04 DOI:10.1002/nbm.5232
Zengwei Xiao, Yujuan Lu, Binzhong He, Pinhuang Tan, Shanshan Wang, Xiaoling Xu, Qiegen Liu
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Abstract

In recent years, diffusion models have made significant progress in accelerating magnetic resonance imaging. Nevertheless, it still has inherent limitations, such as prolonged iteration times and sluggish convergence rates. In this work, we present a novel generalized map generation model based on mean-reverting SDE, called GM-SDE, to alleviate these shortcomings. Notably, the core idea of GM-SDE is optimizing the initial values of the iterative algorithm. Specifically, the training process of GM-SDE diffuses the original k-space data to an intermediary degraded state with fixed Gaussian noise, while the reconstruction process generates the data by reversing this process. Based on the generalized map, three variants of GM-SDE are proposed to learn k-space data with different structural characteristics to improve the effectiveness of model training. GM-SDE also exhibits flexibility, as it can be integrated with traditional constraints, thereby further enhancing its overall performance. Experimental results showed that the proposed method can reduce reconstruction time and deliver excellent image reconstruction capabilities compared to the complete diffusion-based method.

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基于加速磁共振成像广义图的扩散模型
近年来,扩散模型在加速磁共振成像方面取得了重大进展。然而,它仍然存在固有的局限性,如迭代时间长、收敛速度慢等。在这项工作中,我们提出了一种基于均值回复 SDE 的新型广义地图生成模型,称为 GM-SDE,以缓解这些缺陷。值得注意的是,GM-SDE 的核心思想是优化迭代算法的初始值。具体来说,GM-SDE 的训练过程是将原始的 k 空间数据扩散到带有固定高斯噪声的中间退化状态,而重建过程则通过逆转这一过程生成数据。在广义图的基础上,提出了 GM-SDE 的三种变体,以学习具有不同结构特征的 k 空间数据,从而提高模型训练的有效性。GM-SDE 还具有灵活性,可以与传统的约束条件相结合,从而进一步提高其整体性能。实验结果表明,与完全基于扩散的方法相比,所提出的方法可以缩短重建时间,并提供出色的图像重建能力。
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来源期刊
NMR in Biomedicine
NMR in Biomedicine 医学-光谱学
CiteScore
6.00
自引率
10.30%
发文量
209
审稿时长
3-8 weeks
期刊介绍: NMR in Biomedicine is a journal devoted to the publication of original full-length papers, rapid communications and review articles describing the development of magnetic resonance spectroscopy or imaging methods or their use to investigate physiological, biochemical, biophysical or medical problems. Topics for submitted papers should be in one of the following general categories: (a) development of methods and instrumentation for MR of biological systems; (b) studies of normal or diseased organs, tissues or cells; (c) diagnosis or treatment of disease. Reports may cover work on patients or healthy human subjects, in vivo animal experiments, studies of isolated organs or cultured cells, analysis of tissue extracts, NMR theory, experimental techniques, or instrumentation.
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