BCLA CLEAR presbyopia: Management with scleral techniques, lens softening, pharmaceutical and nutritional therapies

IF 4.1 3区 医学 Q1 OPHTHALMOLOGY Contact Lens & Anterior Eye Pub Date : 2024-08-01 DOI:10.1016/j.clae.2024.102191
Shehzad A. Naroo , Craig A. Woods , Raquel Gil-Cazorla , Robert E. Ang , Mariana Collazos , Frank Eperjesi , Michel Guillon , AnnMarie Hipsley , Mitchell A. Jackson , Edwin R. Price , James S. Wolffsohn
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Abstract

The aging eye undergoes the same progressive crosslinking which occurs throughout the body, resulting in increased rigidity of ocular connective tissues including the lens and the sclera which impact ocular functions. This offers the potential for a scleral treatment that is based on restoring normal biomechanical movements. Laser Scleral Microporation is a laser therapy that evaporates fractional areas of crosslinked tissues in the sclera, reducing ocular rigidity over critical anatomical zones of the accommodation apparatus, restoring the natural dynamic range of focus of the eye.

Although controversial and challenged, an alternative theory for presbyopia is Schachar’s theory that suggests a reduction in the space between the ciliary processes and the crystalline lens. Widening of this space with expansion bands has been shown to aid near vision in people with presbyopia, a technique that has been used in the past but seems to be obsolete now.

The use of drugs has been used in the treatment of presbyopia, either to cause pupil miosis to increase depth of focus, or an alteration in refractive error (to induce myopia in one eye to create monovision). Drugs and laser ablation of the crystalline lens have been used with the aim of softening the hardened lens. Poor nutrition and excess exposure to ultraviolet light have been implicated in the onset of presbyopia. Dietary nutritional supplements, lifestyle changes have also been shown to improve accommodation and the question arises whether these could be harnessed in a treatment for presbyopia as well.

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BCLA CLEAR 老花眼:巩膜技术、镜片软化、药物和营养疗法的管理。
衰老的眼睛也会发生与全身相同的渐进性交联,导致包括晶状体和巩膜在内的眼部结缔组织更加僵硬,从而影响眼部功能。这为基于恢复正常生物力学运动的巩膜治疗提供了可能。激光巩膜微孔术是一种激光疗法,它能蒸发巩膜中交联组织的部分区域,降低调节器关键解剖区域的眼球硬度,恢复眼球的自然动态聚焦范围。老花眼的另一种理论是 Schachar 理论,该理论认为睫状突起和晶状体之间的空间缩小,尽管这一理论存在争议和质疑。用膨胀带扩大这一空间已被证明有助于老花眼患者的近距离视力,这种技术过去一直在使用,但现在似乎已经过时了。在治疗老花眼的过程中,也曾使用过药物,或使瞳孔缩小以增加聚焦深度,或改变屈光不正(诱导单眼近视以形成单视)。为了软化硬化的晶状体,还使用了药物和激光消融晶状体的方法。营养不良和过度暴露于紫外线被认为是老花眼发病的原因。膳食营养补充剂和生活方式的改变也被证明可以改善调节能力,那么问题来了,是否也可以利用这些方法来治疗老花眼呢?
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来源期刊
CiteScore
7.60
自引率
18.80%
发文量
198
审稿时长
55 days
期刊介绍: Contact Lens & Anterior Eye is a research-based journal covering all aspects of contact lens theory and practice, including original articles on invention and innovations, as well as the regular features of: Case Reports; Literary Reviews; Editorials; Instrumentation and Techniques and Dates of Professional Meetings.
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