The heart sound classification of congenital heart disease by using median EEMD-Hurst and threshold denoising method.

IF 2.6 4区 医学 Q2 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Medical & Biological Engineering & Computing Pub Date : 2025-01-01 Epub Date: 2024-08-05 DOI:10.1007/s11517-024-03173-1
Xuankai Yang, Jing Sun, Hongbo Yang, Tao Guo, Jiahua Pan, Weilian Wang
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Abstract

Heart sound signals are vital for the machine-assisted detection of congenital heart disease. However, the performance of diagnostic results is limited by noise during heart sound acquisition. A limitation of existing noise reduction schemes is that the pathological components of the signal are weak, which have the potential to be filtered out with the noise. In this research, a novel approach for classifying heart sounds based on median ensemble empirical mode decomposition (MEEMD), Hurst analysis, improved threshold denoising, and neural networks are presented. In decomposing the heart sound signal into several intrinsic mode functions (IMFs), mode mixing and mode splitting can be effectively suppressed by MEEMD. Hurst analysis is adopted for identifying the noisy content of IMFs. Then, the noise-dominated IMFs are denoised by an improved threshold function. Finally, the noise reduction signal is generated by reconstructing the processed components and the other components. A database of 5000 heart sounds from congenital heart disease and normal volunteers was constructed. The Mel spectral coefficients of the denoised signals were used as input vectors to the convolutional neural network for classification to verify the effectiveness of the preprocessing algorithm. An accuracy of 93.8%, a specificity of 93.1%, and a sensitivity of 94.6% were achieved for classifying the normal cases from abnormal one.

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使用中值 EEMD-Hurst 和阈值去噪方法对先天性心脏病进行心音分类。
心音信号对于机器辅助检测先天性心脏病至关重要。然而,诊断结果的性能受到心音采集过程中噪音的限制。现有降噪方案的局限性在于信号中的病理成分较弱,有可能被噪声过滤掉。本研究提出了一种基于中值集合经验模式分解(MEEMD)、赫斯特分析、改进阈值去噪和神经网络的新型心音分类方法。在将心音信号分解为多个本征模式函数(IMF)时,MEEMD 可以有效抑制模式混合和模式分裂。采用 Hurst 分析来识别 IMF 的噪声内容。然后,通过改进的阈值函数对噪声占主导地位的 IMF 进行去噪处理。最后,通过重建处理过的分量和其他分量来生成降噪信号。我们建立了一个包含 5000 个先天性心脏病患者和正常志愿者心音的数据库。去噪信号的梅尔频谱系数被用作卷积神经网络分类的输入向量,以验证预处理算法的有效性。对正常与异常病例进行分类的准确率为 93.8%,特异性为 93.1%,灵敏度为 94.6%。
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来源期刊
Medical & Biological Engineering & Computing
Medical & Biological Engineering & Computing 医学-工程:生物医学
CiteScore
6.00
自引率
3.10%
发文量
249
审稿时长
3.5 months
期刊介绍: Founded in 1963, Medical & Biological Engineering & Computing (MBEC) continues to serve the biomedical engineering community, covering the entire spectrum of biomedical and clinical engineering. The journal presents exciting and vital experimental and theoretical developments in biomedical science and technology, and reports on advances in computer-based methodologies in these multidisciplinary subjects. The journal also incorporates new and evolving technologies including cellular engineering and molecular imaging. MBEC publishes original research articles as well as reviews and technical notes. Its Rapid Communications category focuses on material of immediate value to the readership, while the Controversies section provides a forum to exchange views on selected issues, stimulating a vigorous and informed debate in this exciting and high profile field. MBEC is an official journal of the International Federation of Medical and Biological Engineering (IFMBE).
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