A dependent circular-linear model for multivariate biomechanical data: Ilizarov ring fixator study.

IF 1.6 3区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Statistical Methods in Medical Research Pub Date : 2024-09-01 Epub Date: 2024-08-06 DOI:10.1177/09622802241268654
Priyanka Nagar, Andriette Bekker, Mohammad Arashi, Cor-Jacques Kat, Annette-Christi Barnard
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Abstract

Biomechanical and orthopaedic studies frequently encounter complex datasets that encompass both circular and linear variables. In most cases (i) the circular and linear variables are considered in isolation with dependency between variables neglected and (ii) the cyclicity of the circular variables is disregarded resulting in erroneous decision making. Given the inherent characteristics of circular variables, it is imperative to adopt methods that integrate directional statistics to achieve precise modelling. This paper is motivated by the modelling of biomechanical data, that is, the fracture displacements, that is used as a measure in external fixator comparisons. We focus on a dataset, based on an Ilizarov ring fixator, comprising of six variables. A modelling framework applicable to the six-dimensional joint distribution of circular-linear data based on vine copulas is proposed. The pair-copula decomposition concept of vine copulas represents the dependence structure as a combination of circular-linear, circular-circular and linear-linear pairs modelled by their respective copulas. This framework allows us to assess the dependencies in the joint distribution as well as account for the cyclicity of the circular variables. Thus, a new approach for accurate modelling of mechanical behaviour for Ilizarov ring fixators and other data of this nature is imparted.

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多变量生物力学数据的依赖性圆线性模型:Ilizarov环形固定器研究。
生物力学和整形外科研究经常会遇到包含循环和线性变量的复杂数据集。在大多数情况下,(i) 圆形变量和线性变量被孤立考虑,变量之间的依赖性被忽视;(ii) 圆形变量的周期性被忽视,导致错误的决策。鉴于循环变量的固有特征,必须采用整合方向统计的方法来实现精确建模。本文的灵感来自于生物力学数据建模,即骨折位移,该数据被用作外固定器比较的衡量标准。我们将重点放在基于 Ilizarov 环形固定器的数据集上,该数据集由六个变量组成。基于藤状协方差,我们提出了一个适用于圆线性数据六维联合分布的建模框架。藤状协方差的对协方差分解概念将依赖结构表示为由各自协方差建模的圆线性、圆环形和线性线性对的组合。通过这一框架,我们可以评估联合分布中的依赖关系,并考虑循环变量的周期性。因此,我们为精确模拟伊利扎洛夫环形固定器的机械行为和其他此类数据提供了一种新方法。
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来源期刊
Statistical Methods in Medical Research
Statistical Methods in Medical Research 医学-数学与计算生物学
CiteScore
4.10
自引率
4.30%
发文量
127
审稿时长
>12 weeks
期刊介绍: Statistical Methods in Medical Research is a peer reviewed scholarly journal and is the leading vehicle for articles in all the main areas of medical statistics and an essential reference for all medical statisticians. This unique journal is devoted solely to statistics and medicine and aims to keep professionals abreast of the many powerful statistical techniques now available to the medical profession. This journal is a member of the Committee on Publication Ethics (COPE)
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