Machine learning and deep learning tools for the automated capture of cancer surveillance data.

Elizabeth Hsu, Heidi Hanson, Linda Coyle, Jennifer Stevens, Georgia Tourassi, Lynne Penberthy
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Abstract

The National Cancer Institute and the Department of Energy strategic partnership applies advanced computing and predictive machine learning and deep learning models to automate the capture of information from unstructured clinical text for inclusion in cancer registries. Applications include extraction of key data elements from pathology reports, determination of whether a pathology or radiology report is related to cancer, extraction of relevant biomarker information, and identification of recurrence. With the growing complexity of cancer diagnosis and treatment, capturing essential information with purely manual methods is increasingly difficult. These new methods for applying advanced computational capabilities to automate data extraction represent an opportunity to close critical information gaps and create a nimble, flexible platform on which new information sources, such as genomics, can be added. This will ultimately provide a deeper understanding of the drivers of cancer and outcomes in the population and increase the timeliness of reporting. These advances will enable better understanding of how real-world patients are treated and the outcomes associated with those treatments in the context of our complex medical and social environment.

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用于自动获取癌症监测数据的机器学习和深度学习工具。
美国国家癌症研究所和能源部的战略合作伙伴关系应用先进的计算和预测性机器学习和深度学习模型,自动从非结构化临床文本中获取信息,以便纳入癌症登记册。应用包括从病理报告中提取关键数据元素、确定病理或放射报告是否与癌症有关、提取相关生物标记信息以及识别复发。随着癌症诊断和治疗的复杂性不断增加,用纯手工方法获取重要信息变得越来越困难。这些应用先进计算能力自动提取数据的新方法为弥补关键信息差距提供了机会,并创建了一个灵活机动的平台,可在此基础上添加基因组学等新信息源。这最终将使人们更深入地了解癌症的驱动因素和人群中的结果,并提高报告的及时性。在复杂的医疗和社会环境下,这些进步将使人们能够更好地了解现实世界中的患者是如何接受治疗的,以及与这些治疗相关的结果。
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