Targeted mutagenesis in Arabidopsis and medicinal plants using transposon-associated TnpB

IF 9.3 1区 生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Journal of Integrative Plant Biology Pub Date : 2024-08-07 DOI:10.1111/jipb.13758
Zongyou Lv, Wenhua Chen, Shiyuan Fang, Boran Dong, Xingxing Wang, Lida Zhang, Jingshi Xue, Wansheng Chen
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Abstract

The programmable nuclease TnpB is significantly smaller than Cas9, can edit genes in medicinal plants, including Artemisia annua, Salvia miltiorrhiza, Scutellaria baicalensis, Isatis indigotica, and Codonopsis pilosula, and has potential uses in molecular breeding to enhance crop yield and quality.

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利用转座子相关 TnpB 在拟南芥和药用植物中进行定向诱变。
可编程核酸酶 TnpB 比 Cas9 小得多,可以编辑药用植物(包括黄花蒿、丹参、黄芩、菘蓝和党参)中的基因,并有可能用于分子育种,以提高作物的产量和质量。
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来源期刊
Journal of Integrative Plant Biology
Journal of Integrative Plant Biology 生物-生化与分子生物学
CiteScore
18.00
自引率
5.30%
发文量
220
审稿时长
3 months
期刊介绍: Journal of Integrative Plant Biology is a leading academic journal reporting on the latest discoveries in plant biology.Enjoy the latest news and developments in the field, understand new and improved methods and research tools, and explore basic biological questions through reproducible experimental design, using genetic, biochemical, cell and molecular biological methods, and statistical analyses.
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