Association between adolescent depression and adult suicidal behavior: A systematic review and meta-analysis

IF 3.8 4区 医学 Q1 PSYCHIATRY Asian journal of psychiatry Pub Date : 2024-07-29 DOI:10.1016/j.ajp.2024.104185
Cong Wang , Yingying Tong , Ting Tang , Xinhui Wang , Lulu Fang , Xue Wen , Puyu Su , Jun Wang , Gengfu Wang
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Abstract

This meta-analysis aims to estimate the association between adolescent depression and adult suicidal behavior, while systematically evaluating gender differences reported in literature. A random-effects model was used to determine the pooled association, reporting odds ratios (ORs) with corresponding 95 % confidence intervals (CIs). Nine articles comprising over 6084 adolescents together showed that people with a history of depression in adolescence are more likely to gain suicidal behaviors during adulthood (OR = 3.97, 95 % Cl: 2.79, 5.63). Sex-specific analysis indicated that males who experienced depression in adolescence developed a higher incidence of suicidal behavior in adulthood compared to females with a similar history (Males: OR = 3.61, 95 % Cl: 1.02, 12.78; Females: OR = 3.56, 95 % Cl: 1.71, 7.43). Furthermore, suicide attempts emerged as the predominant outcome among various suicidal behaviors (OR = 3.43, 95 % Cl: 1.75, 6.71). This meta-analysis provides robust evidence that depression in adolescence significantly increases the risk of suicidal behavior in adulthood.

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青少年抑郁与成人自杀行为之间的关系:系统回顾和荟萃分析。
这项荟萃分析旨在估算青少年抑郁症与成年自杀行为之间的关联,同时系统评估文献中报道的性别差异。研究采用随机效应模型来确定两者之间的关联,并报告了几率比(ORs)和相应的 95 % 置信区间(CIs)。由超过 6084 名青少年共同参与的九篇文章显示,青少年时期有抑郁症病史的人在成年后更有可能出现自杀行为(OR = 3.97,95 % Cl:2.79, 5.63)。性别特异性分析表明,与有类似病史的女性相比,在青春期患过抑郁症的男性在成年后出现自杀行为的几率更高(男性:OR = 3.61,95 % Cl:2.79,5.63):男性:OR = 3.61,95 % Cl:1.02,12.78;女性:OR = 3.56,95 % Cl:1.02,12.78:男性:OR = 3.61,95% Cl:1.02,12.78;女性:OR = 3.56,95% Cl:1.71,7.43)。此外,自杀未遂是各种自杀行为的主要结果(OR = 3.43,95% Cl:1.75,6.71)。这项荟萃分析提供了强有力的证据,证明青少年时期的抑郁症会显著增加成年后自杀行为的风险。
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来源期刊
Asian journal of psychiatry
Asian journal of psychiatry Medicine-Psychiatry and Mental Health
CiteScore
12.70
自引率
5.30%
发文量
297
审稿时长
35 days
期刊介绍: The Asian Journal of Psychiatry serves as a comprehensive resource for psychiatrists, mental health clinicians, neurologists, physicians, mental health students, and policymakers. Its goal is to facilitate the exchange of research findings and clinical practices between Asia and the global community. The journal focuses on psychiatric research relevant to Asia, covering preclinical, clinical, service system, and policy development topics. It also highlights the socio-cultural diversity of the region in relation to mental health.
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