Analysis of visual quality improvement after implantation of PanOptix trifocal intraocular lens in cataract patients with different axial lengths.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-07-15 eCollection Date: 2024-01-01 DOI:10.62347/FRJZ4885
Yin-Ping Yang, Ya Tan, Qiong Liao
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Abstract

Objective: To assess the visual quality, both subjective and objective, of cataract patients with varying axial lengths (AL) after PanOptix trifocal intraocular lens (IOL) implantation and investigated the lens tilt and its correlation with visual outcomes.

Methods: From July 2020 to June 2022, 70 patients (140 eyes) diagnosed with age-related cataracts and undergoing PanOptix implantation at Chongqing Eye and Vision Care Hospital, Aier Eye Hospital Group, were included. Patients were assigned to either the observation group (35 cases, 70 eyes with PanOptix trifocal IOL) or the control group (35 cases, 70 eyes with bifocal IOL). Patients were further subdivided based on AL into AL < 24 mm (observation group: 23 eyes; control group: 26 eyes) and AL ≥ 24 mm (observation group: 47 eyes; control group: 44 eyes). Postoperative follow-up lasted three months. Visual acuity (distant, intermediate, near), objective visual quality (Strehl ratio: SR, total eye modulation transfer function (MTF)), and visual aberrations were measured preoperatively and at 3 months post-operation.

Results: Postoperatively, all groups saw significant improvements in uncorrected distance visual acuity (UCDVA), uncorrected intermediate visual acuity (UCIVA), and uncorrected near visual acuity (UCNVA) compared to preoperative values (T0) (all P < 0.05). Notably, UCIVA was significantly better in the observation group than in the control group (P < 0.05). At three months (T1), reductions in total high-order aberration (tHOA), internal high-order aberration (iHOA), coma, and trefoil aberrations were observed in both groups compared to baseline, with more significant decreases in the observation group (all P < 0.05). Both SR and MTF cutoff showed marked improvement from T0 to T1, with the observation group experiencing greater enhancements (both P < 0.05). The defocus curve of the observation group showed a gentle slope between +0.5 D and -3.0 D, maintaining superior visual acuity compared to the control group (P < 0.05). Subjective visual quality scores at T1 were significantly higher than at T0 for both groups (P < 0.05), with patients in the observation group scoring higher than those in the control group across all AL categories (P < 0.05). Spearman correlation analysis indicated that the tilt after PanOptix trifocal IOL implantation was associated with tHOA (r = 0.273, P = 0.022), iHOA (r = 0.433, P < 0.001), Trefoil (r = 0.360, P = 0.002) and coma (r = 0.688, P < 0.001).

Conclusion: PanOptix trifocal IOL implantation in cataract patients across different AL significantly enhances visual quality compared to bifocal IOLs, suggesting a strong case for its clinical adoption.

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不同轴长白内障患者植入 PanOptix 三焦点眼内透镜后视觉质量改善情况分析。
目的评估不同轴长(AL)的白内障患者在PanOptix三焦点眼内人工晶体(IOL)植入术后的主观和客观视觉质量,并研究晶状体倾斜度及其与视觉结果的相关性:纳入2020年7月至2022年6月期间,在重庆爱尔眼科医院集团重庆眼视光医院接受PanOptix人工晶体植入术的70例(140眼)老年性白内障患者。患者被分配到观察组(35 例,70 眼,植入 PanOptix 三焦点人工晶体)或对照组(35 例,70 眼,植入双焦点人工晶体)。根据AL值将患者进一步细分为AL值小于24毫米(观察组:23眼;对照组:26眼)和AL值≥24毫米(观察组:47眼;对照组:44眼)。术后随访三个月。视力(远、中、近)、客观视觉质量(Strehl ratio:术前和术后 3 个月测量视力(远、中、近)、客观视觉质量(Strehl 比率:SR、全眼调制传递函数(MTF))和视像差:结果:与术前值(T0)相比,术后各组的未矫正远视力(UCDVA)、未矫正中视力(UCIVA)和未矫正近视力(UCNVA)均有明显改善(P均<0.05)。值得注意的是,观察组的 UCIVA 明显优于对照组(P < 0.05)。三个月后(T1),与基线相比,两组的总高阶像差(tHOA)、内高阶像差(iHOA)、昏迷和三叶形像差均有所下降,其中观察组的下降幅度更大(均为 P < 0.05)。从 T0 到 T1,SR 和 MTF 截止值都有明显改善,观察组的改善幅度更大(均为 P <0.05)。观察组的离焦曲线在 +0.5 D 和 -3.0 D 之间呈现出平缓的斜率,与对照组相比保持了较好的视力(P < 0.05)。两组患者在 T1 期的主观视觉质量评分均明显高于 T0 期(P < 0.05),观察组患者在所有 AL 类别的评分均高于对照组(P < 0.05)。斯皮尔曼相关性分析表明,植入 PanOptix 三焦点人工晶体后的倾斜度与 tHOA(r = 0.273,P = 0.022)、iHOA(r = 0.433,P < 0.001)、Trefoil(r = 0.360,P = 0.002)和昏迷(r = 0.688,P < 0.001)相关:结论:与双焦点人工晶体相比,在不同AL的白内障患者中植入PanOptix三焦点人工晶体可显著提高视觉质量,因此有充分理由在临床上采用这种人工晶体。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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