{"title":"Correlates of symptom burden in renal dialysis patients: a systematic review and meta-analysis.","authors":"Yifan Lu, Shuqi Zhai, Qinqin Liu, Congcong Dai, Shejuan Liu, Yanqing Shang, Chaoran Chen","doi":"10.1080/0886022X.2024.2382314","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Patients receiving renal dialysis often experience a wide range of symptoms. These symptoms contribute to a significant symptom burden that significantly affects patients' quality of life and serves as a significant predictor of healthcare resource utilization and patient prognosis. It is necessary to synthesize existing evidence to draw reliable conclusions to deepen the understanding of symptom burden.</p><p><strong>Objective: </strong>A systematic review and meta-analysis were conducted to identify the relevant factors of symptom burden in patients receiving renal dialysis.</p><p><strong>Methods: </strong>The systematic review and meta-analysis was conducted by searching nine databases for studies reporting the correlates between symptom burden and demographic variables, disease factors, and psychosocial factors from inception to 24 June 2024. After two researchers independently conducted literature search, data extraction, and quality evaluation, meta-analysis was conducted using R Language and Stata 15.1 Software. This study has been registered in the PROSPERO.</p><p><strong>Results: </strong>Sixty-two studies were included in this review. Results showed that the symptom burden of renal dialysis patients was positively correlated with age, gender, working status, medical cost, dialysis age, quality of sleep, nutritional status, comorbidities, depression, anxiety, disease uncertain, avoidance coping and resignation coping, and negatively correlated with marital status, income, serum sodium, quality of life, social support, subjective well-being, and self-management ability.</p><p><strong>Conclusions: </strong>Our findings reveal that many factors, including demographic, disease-related, and psychosocial variables, affect symptom burden. The results can supply information for health promotion and relief symptom burden for patients receiving renal dialysis.<b>Registered number:</b> CRD42024507577.</p>","PeriodicalId":20839,"journal":{"name":"Renal Failure","volume":null,"pages":null},"PeriodicalIF":3.0000,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11312985/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Renal Failure","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/0886022X.2024.2382314","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/8/8 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
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Abstract
Background: Patients receiving renal dialysis often experience a wide range of symptoms. These symptoms contribute to a significant symptom burden that significantly affects patients' quality of life and serves as a significant predictor of healthcare resource utilization and patient prognosis. It is necessary to synthesize existing evidence to draw reliable conclusions to deepen the understanding of symptom burden.
Objective: A systematic review and meta-analysis were conducted to identify the relevant factors of symptom burden in patients receiving renal dialysis.
Methods: The systematic review and meta-analysis was conducted by searching nine databases for studies reporting the correlates between symptom burden and demographic variables, disease factors, and psychosocial factors from inception to 24 June 2024. After two researchers independently conducted literature search, data extraction, and quality evaluation, meta-analysis was conducted using R Language and Stata 15.1 Software. This study has been registered in the PROSPERO.
Results: Sixty-two studies were included in this review. Results showed that the symptom burden of renal dialysis patients was positively correlated with age, gender, working status, medical cost, dialysis age, quality of sleep, nutritional status, comorbidities, depression, anxiety, disease uncertain, avoidance coping and resignation coping, and negatively correlated with marital status, income, serum sodium, quality of life, social support, subjective well-being, and self-management ability.
Conclusions: Our findings reveal that many factors, including demographic, disease-related, and psychosocial variables, affect symptom burden. The results can supply information for health promotion and relief symptom burden for patients receiving renal dialysis.Registered number: CRD42024507577.
背景：接受肾透析的患者经常会出现各种症状。这些症状造成了严重的症状负担，严重影响了患者的生活质量，是医疗资源使用和患者预后的重要预测因素。有必要综合现有证据得出可靠结论，以加深对症状负担的理解：通过系统回顾和荟萃分析，确定肾透析患者症状负担的相关因素：系统性回顾和荟萃分析通过检索九个数据库，寻找从开始到2024年6月24日期间报告症状负担与人口统计学变量、疾病因素和社会心理因素之间相关性的研究。两名研究人员独立进行文献检索、数据提取和质量评估后，使用 R 语言和 Stata 15.1 软件进行了荟萃分析。本研究已在 PROSPERO.Results 中注册：本综述共纳入 62 项研究。结果显示，肾透析患者的症状负担与年龄、性别、工作状况、医疗费用、透析年龄、睡眠质量、营养状况、合并症、抑郁、焦虑、疾病不确定性、回避应对和辞职应对呈正相关，与婚姻状况、收入、血清钠、生活质量、社会支持、主观幸福感和自我管理能力呈负相关：我们的研究结果表明，人口统计学、疾病相关变量和心理社会变量等多种因素都会影响症状负担。结论：我们的研究结果表明，包括人口统计学、疾病相关变量和心理社会变量在内的许多因素都会影响症状负担，这些结果可为促进肾透析患者的健康和减轻其症状负担提供信息：CRD42024507577。
期刊介绍：
Renal Failure primarily concentrates on acute renal injury and its consequence, but also addresses advances in the fields of chronic renal failure, hypertension, and renal transplantation. Bringing together both clinical and experimental aspects of renal failure, this publication presents timely, practical information on pathology and pathophysiology of acute renal failure; nephrotoxicity of drugs and other substances; prevention, treatment, and therapy of renal failure; renal failure in association with transplantation, hypertension, and diabetes mellitus.
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