Wan Lan Jiang, Ting Xu, Bi Qing Zhang, Lu Zhang, Min Wu, Wen Xie
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Abstract
Objectives: Baker's cyst (BC) is a complex complication of rheumatoid arthritis (RA), with a poor prognosis. This paper aimed to analyse the clinical features and risk factors for BC in patients with RA to assist clinicians in early warning and appropriate action.
Methods: The clinical features of the hospitalized RA patients with knee affected were analysed retrospectively. The R software was used for the statistical analysis, while logistic regression analyses were used to determine independent risk factors.
Results: A total of 367 RA patients with knee affected were studied, and BC was diagnosed in 15.3% of them. The BC group exhibited a higher proportion of knee-only affected than the non-BC group (P < .05), while the attributes linked to disease activity exhibited no disparity. Logistic regression analyses selected two independent risk factors for BC: knee-only affected and anaemia. A total of 26.8% of patients with BC developed rupture, exhibiting a higher proportion of knee-only affected (P < .05), compared to those unruptured.
Conclusions: The occurrence and rupture of BC in RA patients were significantly related to local inflammation, but not to systemic one. Incorporating local treatment may be a more advantageous option compared to solely relying on systemic therapy.
目的：贝克氏囊肿（BC）是类风湿性关节炎（RA）的一种复杂并发症，预后较差。本文旨在分析 RA 患者 BC 的临床特征和风险因素，以帮助临床医生早期预警并采取适当措施：方法：对住院的膝关节受累的 RA 患者的临床特征进行回顾性分析。采用 R 软件进行统计分析，并通过逻辑回归分析确定独立的风险因素：共研究了 367 例膝关节受累的 RA 患者，其中 15.3% 确诊为 BC。BC组膝关节受累的比例高于非BC组（P＜0.05），而与疾病活动性相关的属性则无差异。逻辑回归分析选出了 BC 的两个独立风险因素：单纯膝关节受累和贫血。26.8%的BC患者出现破裂，与未破裂者相比，仅膝关节受累的比例更高（P < 0.05）：结论：RA患者BC的发生和破裂与局部炎症明显相关，但与全身炎症无关。结论：RA 患者 BC 的发生和破裂与局部炎症密切相关，而与全身炎症无关。与单纯依赖全身治疗相比，结合局部治疗可能是更有利的选择。
期刊介绍：
Modern Rheumatology publishes original papers in English on research pertinent to rheumatology and associated areas such as pathology, physiology, clinical immunology, microbiology, biochemistry, experimental animal models, pharmacology, and orthopedic surgery.
Occasional reviews of topics which may be of wide interest to the readership will be accepted. In addition, concise papers of special scientific importance that represent definitive and original studies will be considered.
Modern Rheumatology is currently indexed in Science Citation Index Expanded (SciSearch), Journal Citation Reports/Science Edition, PubMed/Medline, SCOPUS, EMBASE, Chemical Abstracts Service (CAS), Google Scholar, EBSCO, CSA, Academic OneFile, Current Abstracts, Elsevier Biobase, Gale, Health Reference Center Academic, OCLC, SCImago, Summon by Serial Solutions
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