Microwave Synthesis of Fluorescent Carbon Quantum dots from Araucaria Heterophylla Gum: Application in Drug Detection.

IF 2.6 4区 化学 Q2 BIOCHEMICAL RESEARCH METHODS Journal of Fluorescence Pub Date : 2024-08-10 DOI:10.1007/s10895-024-03874-8
Rohitash Kumar, Vimal K Bhardwaj
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Abstract

This study employed a green microwave synthesis technique to produce carbon quantum dots (CQDs) from araucaria heterophylla gum extract. The produced CQDs emit a distinct blue fluorescent light, contributing a remarkable quantum yield of 14.69%. Their average particle size measures at 1.62 ± 0.39 nm. Furthermore, these CQDs demonstrate excellent water solubility and maintain high fluorescence stability despite ionic strength, pH and time variations. Moreover, we present here for the first time that the synthesized CQDs demonstrate a rapid, exceptionally sensitive, and discerning fluorescence quenching phenomenon (IFE) concerning Cefprozil (CPR). The fluorescent probe was sensitive and specific with good linear relationships for CPR in the 0-18 µM range. The limit of detection for relationships for CPR was 2.51 µM. This study provides novel opportunities for producing high-quality luminescent CQDs that meet the requirements for various biological and environmental applications.

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用微波从 Araucaria Heterophylla 胶中合成荧光碳量子点:在药物检测中的应用。
本研究采用绿色微波合成技术,从紫苏树胶提取物中制备碳量子点(CQDs)。所制备的 CQDs 发出明显的蓝色荧光,量子产率高达 14.69%。它们的平均粒径为 1.62 ± 0.39 nm。此外,这些 CQDs 还具有极佳的水溶性,并能在离子强度、pH 值和时间变化的情况下保持较高的荧光稳定性。此外,我们在此首次展示了合成的 CQDs 对头孢丙烯(CPR)的快速、异常灵敏和辨别力极强的荧光淬灭现象(IFE)。该荧光探针对 0-18 µM 范围内的 CPR 具有良好的线性关系,灵敏度高,特异性强。CPR 的检测限为 2.51 µM。这项研究为生产符合各种生物和环境应用要求的高质量发光 CQD 提供了新的机遇。
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来源期刊
Journal of Fluorescence
Journal of Fluorescence 化学-分析化学
CiteScore
4.60
自引率
7.40%
发文量
203
审稿时长
5.4 months
期刊介绍: Journal of Fluorescence is an international forum for the publication of peer-reviewed original articles that advance the practice of this established spectroscopic technique. Topics covered include advances in theory/and or data analysis, studies of the photophysics of aromatic molecules, solvent, and environmental effects, development of stationary or time-resolved measurements, advances in fluorescence microscopy, imaging, photobleaching/recovery measurements, and/or phosphorescence for studies of cell biology, chemical biology and the advanced uses of fluorescence in flow cytometry/analysis, immunology, high throughput screening/drug discovery, DNA sequencing/arrays, genomics and proteomics. Typical applications might include studies of macromolecular dynamics and conformation, intracellular chemistry, and gene expression. The journal also publishes papers that describe the synthesis and characterization of new fluorophores, particularly those displaying unique sensitivities and/or optical properties. In addition to original articles, the Journal also publishes reviews, rapid communications, short communications, letters to the editor, topical news articles, and technical and design notes.
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