Al and MCPD in grain products in Gansu province, China and risk assessment.

IF 2.5 3区农林科学 Q2 CHEMISTRY, APPLIED Food additives & contaminants. Part B, Surveillance Pub Date : 2024-12-01 Epub Date: 2024-08-12 DOI:10.1080/19393210.2024.2382222

Ping Wang, Gexiang Zhang

引用次数: 0

Abstract

This study conducted a dietary exposure assessment of chloropropanols and aluminium, after quantifying their content in food. The mean dietary exposure to Al from total grain products was found to be 6.4E-04 mg/kg bw/week, not exceeding the provisional tolerable weekly intake (PTWI). The results showed that the mean dietary exposure of 3-monochloro-1,2-propanediol (3-MCPD) from grain products was higher than the tolerable daily intake (TDI). Deterministic evaluations showed that the mean HQ of 1.5 to Al from fried dough twist was higher than 1. However, the HI values to Al were lower than 1 and the Monte Carlo simulation (MCS) showed that the HQ was greater than 1 at the 99% exposure level. Deterministic and probabilistic methods indicated that HQ values of 3-MCPD from grain products were above 1, whereas the mean HI value was 0.62.

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中国甘肃省粮食产品中的 Al 和 MCPD 含量及风险评估。

这项研究在对食物中的氯丙醇和铝含量进行量化后，对从膳食中摄入氯丙醇和铝的情况进行了评估。结果发现，从全部谷物产品中摄入铝的平均膳食摄入量为 6.4E-04 毫克/千克体重/周，不超过暂定每周可容忍摄入量（PTWI）。结果显示，从谷物产品摄取 3-氯丙二醇的平均膳食摄入量，高于每日可容忍摄入量。确定性评估显示，从油炸面团麻花摄取铝的平均 HQ 值为 1.5，高于 1，但摄取铝的 HI 值则低于 1，而蒙特卡罗模拟（MCS）显示，在 99% 的摄取量水平下，HQ 值高于 1。确定性和概率方法都显示，谷物产品中氯丙二醇的 HQ 值高于 1，而平均 HI 值则为 0.62。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Food additives & contaminants. Part B, Surveillance 农林科学-毒理学

CiteScore

5.30

自引率

10.30%

发文量

审稿时长

2.7 months

期刊介绍： Food Additives & Contaminants: Part B publishes surveillance data indicating the presence and levels of occurrence of designated food additives, residues and contaminants in foods, food supplements and animal feed. Data using validated methods must meet stipulated quality standards to be acceptable and must be presented in a prescribed format for subsequent data-handling. Food Additives & Contaminants: Part B restricts its scope to include certain classes of food additives, residues and contaminants. This is based on a goal of covering those areas where there is a need to record surveillance data for the purposes of exposure and risk assessment. The scope is initially restricted to: Additives - food colours, artificial sweeteners, and preservatives; Residues – veterinary drug and pesticide residues; Contaminants – metals, mycotoxins, phycotoxins, plant toxins, nitrate/nitrite, PCDDs/PCFDs, PCBs, PAHs, acrylamide, 3-MPCD and contaminants derived from food packaging. Readership: The readership includes scientists involved in all aspects of food safety and quality and particularly those involved in monitoring human exposure to chemicals from the diet. Papers reporting surveillance data in areas other than the above should be submitted to Part A . The scope of Part B will be expanded from time-to-time to ensure inclusion of new areas of concern.