[Wernicke encephalopathy : a neuro-ophthalmological side effect of bariatric surgery].

Revue medicale de Liege Pub Date : 2024-07-01
Solène Kairis, Cécile Andris, Jean-Marie Rakic
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Abstract

Due to an increase in the worldwide prevalence of obesity and the efficiency of bariatric surgery, this procedure is more often performed. Besides its benefits, it has also disadvantages and may be the cause of nutritional deficiencies. Thiamin deficiency is particularly important to diagnose and to treat early as it can lead to major sequelae and even to death. Wernicke's encephalopathy is the most frequent presentation associating confusion, ataxia, ophtalmoplegia and nystagmus. The full triad is not usually observed, which may lead to sub-diagnosis of this affection. The diagnosis is clinical, biological and radiologic thanks to the brain MRI. Intravenous thiamin supplementation therapy must be administered as fast as possible in order to avoid long-term damages. In the ophthalmological field, the potential sequelae are ophthalmoplegia, nystagmus and optic neuropathy. Therapeutics for nystagmus are pharmacological, surgical and/or optical. We illustrate this condition with a case report of an 18-year-old man developing Wernicke's encephalopathy as early as six weeks after a sleeve gastrectomy.

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[韦尼克脑病:减肥手术的神经眼科副作用]。
由于世界范围内肥胖症发病率的增加和减肥手术的高效性,这种手术越来越常见。肥胖症除了有好处外,也有坏处,可能会导致营养缺乏。硫胺素缺乏症的诊断和早期治疗尤为重要,因为它会导致重大后遗症,甚至死亡。Wernicke脑病是最常见的表现,伴有意识模糊、共济失调、视神经麻痹和眼球震颤。通常不会观察到完整的三联征,这可能会导致对这种疾病的误诊。通过脑部核磁共振成像可进行临床、生物学和放射学诊断。必须尽快进行静脉补充硫胺素治疗,以避免长期损害。在眼科领域,潜在的后遗症有眼球震颤、眼球震颤和视神经病变。眼球震颤的治疗方法有药物治疗、手术治疗和/或光学治疗。一名 18 岁的男子在接受袖状胃切除术六周后就患上了韦尼克脑病,我们通过该病例报告对此进行了说明。
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